SNW1 抗体 (N-Term)
Quick Overview for SNW1 抗体 (N-Term) (ABIN182523)
抗原
See all SNW1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- RQGQSKDKVI YSKYTDLVPK EVMNADDPDL QRPDEEAIKE ITEKTRVALE
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 83%
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产品特性
- This is a rabbit polyclonal antibody against SKIIP. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human SKIIP
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anti-SNW Domain Containing 1 (SNW1) antibody
SNW1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SNW Domain Containing 1 (SNW1) (AA 300-536) antibodySNW1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SNW Domain Containing 1 (SNW1) (AA 464-497) antibodySNW1 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal RB54232 unconjugated
anti-SNW Domain Containing 1 (SNW1) (AA 103-152) antibodySNW1 适用: 人, 小鼠, 犬, Cow, 马, Pig, 兔, 大鼠, Hamster, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-SNW Domain Containing 1 (SNW1) (N-Term) antibodySNW1 适用: 人, 小鼠, 犬, Cow, 马, Pig, 兔, 大鼠, 豚鼠, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 536 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SNW1 (SNW Domain Containing 1 (SNW1))
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别名
- SKIIP
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背景
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SKIIP (Nuclear Protein SkiP, nuclear receptor coactivator NCoA-62, ski-interacting protein) is a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also interact with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity.
Alias Symbols: Bx42, SKIP, Prp45, SKIIP, PRPF45, NCOA-62
Protein Interaction Partner: TRAF1, GOLGA2, KRT40, LZTS2, RINT1, TEX11, CEP55, PPIL1, TFIP11, MTUS2, IKZF1, TP53, TUBGCP3, AURKB, UBC, SUZ12, RNF2, BMI1, HECW2, HDAC11, Dlg4, TTC14, ZNF830, SNIP1, CXorf56, XAB2, CTNNBL1, SART1, NHP2L1, MFAP1, EIF4A3, MAGOH, DHX15, DDX5, PABPC1, SKIV2
Protein Size: 536 -
分子量
- 61 kDa
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基因ID
- 22938
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NCBI登录号
- NM_012245, NP_036377
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UniProt
- Q13573
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途径
- Retinoic Acid Receptor Signaling Pathway
抗原
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