OPTN 抗体 (N-Term)
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北京 101111
Quick Overview for OPTN 抗体 (N-Term) (ABIN2779546)
抗原
See all OPTN 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- OPTN Antibody - N-terminal region
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序列
- LSAWTEKQKE ERQFFEIQSK EAKERLMALS HENEKLKEEL GKLKGKSERS
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预测反应
- Cow: 79%, Dog: 79%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 79%, Rabbit: 93%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against OPTN. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human OPTN
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anti-Optineurin (OPTN) antibody
KD Validated OPTN 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB4715 unconjugated Recombinant Antibody
anti-Optineurin (OPTN) (AA 241-577) antibodyOPTN 适用: 人, 小鼠, 大鼠 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Optineurin (OPTN) (AA 341-440) antibodyOPTN 适用: 人 WB, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Optineurin (OPTN) (AA 1-300) antibodyOPTN 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Optineurin (OPTN) antibodyOPTN 适用: 人 WB, IP, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Optineurin (OPTN) (AA 1-577) antibodyOPTN 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Optineurin (OPTN) (AA 1-577) antibodyOPTN 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Optineurin (OPTN) (AA 559-575) antibodyOPTN 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Optineurin (OPTN) (AA 575-591) antibodyOPTN 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Optineurin (OPTN) (AA 1-577) antibodyOPTN 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP32292-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- OPTN (Optineurin (OPTN))
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别名
- OPTN
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背景
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Background Information: OPTN is the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein.
Gene Name: Optineurin
Alternative Symbols: NRP, FIP2, HIP7, HYPL, ALS12, GLC1E, TFIIIA-INTP
Protein Name: Optineurin
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分子量
- 66kDa
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基因ID
- 10133
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NCBI登录号
- NP_001008214
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UniProt
- Q96CV9
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途径
- M Phase
抗原
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