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ESR2 抗体 (Middle Region)

This anti-ESR2 antibody is a 兔 多克隆 antibody detecting ESR2 in WB. Suitable for 人, 小鼠, 大鼠, 绵羊, Pig, 马, 犬, Cow, 兔, 豚鼠 和 山羊.
产品编号 ABIN2779528
发货至: 中国

Quick Overview for ESR2 抗体 (Middle Region) (ABIN2779528)

抗原

See all ESR2 抗体
ESR2 (Estrogen Receptor 2 (ESR2))

适用

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人, 小鼠, 大鼠, 绵羊, Pig, 马, 犬, Cow, 兔, 豚鼠, 山羊

宿主

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克隆类型

  • 162
  • 48
多克隆

标记

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This ESR2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Middle Region

    序列

    EYLCVKAMIL LNSSMYPLVT ATQDADSSRK LAHLLNAVTD ALVWVIAKSG

    预测反应

    Cow: 86%, Dog: 86%, Goat: 86%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 86%, Rat: 86%, Sheep: 86%

    产品特性

    This is a rabbit polyclonal antibody against ESR2. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human ESR2
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 530 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    ESR2 (Estrogen Receptor 2 (ESR2))

    别名

    ESR2

    背景

    ESR2 is a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. It contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized.This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized.
    Alias Symbols: ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2
    Protein Interaction Partner: PLSCR1, MEOX2, NOTCH2NL, RFX6, MMS19, BCAS2, NCOA1, RPS18, MRPS15, MRPS22, ZC3HAV1, PTCD3, EXOSC4, MRPS2, MED4, MRPS27, MRPS31, MED17, TRIM24, NRIP1, NCOA3, STAU1, SP1, PABPC5, MYLK2, RPS11, RPS4X, RPLP0, RPL36AL, PPP5C, HSPA8, ESR2, ESR1, ACTB, SRA1, ARI
    Protein Size: 530

    分子量

    59 kDa

    基因ID

    2100

    NCBI登录号

    NM_001437, NP_001428

    UniProt

    Q92731

    途径

    Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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