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DVL2 抗体 (N-Term)

This anti-DVL2 antibody is a 兔 多克隆 antibody detecting DVL2 in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, 豚鼠, 马, 兔 和 Saccharomyces cerevisiae. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2779458
发货至: 中国

Quick Overview for DVL2 抗体 (N-Term) (ABIN2779458)

抗原

See all DVL2 抗体
DVL2 (Dishevelled, Dsh Homolog 2 (Drosophila) (DVL2))

适用

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人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, 豚鼠, 马, 兔, Saccharomyces cerevisiae

宿主

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克隆类型

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多克隆

标记

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This DVL2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    N-Term

    序列

    AGSSTGGGGV GETKVIYHLD EEETPYLVKI PVPAERITLG DFKSVLQRPA

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 82%, Zebrafish: 93%

    产品特性

    This is a rabbit polyclonal antibody against DVL2. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human DVL2
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 736 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Lee, Zhao, Moon, Yoon, Kim, An, Kwon, Hwang, Choi, Shim, Kim, Yang: "Differential involvement of GABA system in mediating behavioral and neurochemical effect of acupuncture in ethanol-withdrawn rats." in: Neuroscience letters, Vol. 443, Issue 3, pp. 213-7, (2008) (PubMed).

  • 抗原

    DVL2 (Dishevelled, Dsh Homolog 2 (Drosophila) (DVL2))

    别名

    DVL2

    背景

    DVL2 is a member of the dishevelled (dsh) protein family. It is a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans. This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40 % amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: -
    Protein Interaction Partner: UBC, NUMA1, IQGAP1, DVL3, DVL1, RNF185, WWOX, SQSTM1, IRS2, IRS1, TARS, GABARAPL1, CSNK1E, OTULIN, TP53, LYN, Smurf2, PLA2G12A, CTBP2, LRRK2, ATN1, RBFOX1, ITCH, ELAVL1, NHLRC1, MAP1LC3A, GABARAP, VHL, SIRT1, VANGL1, TCEB3B, CPSF7, SNF8, PPM1A, POLI, DYNL
    Protein Size: 736

    分子量

    79 kDa

    基因ID

    1856

    NCBI登录号

    NM_004422, NP_004413

    UniProt

    O14641

    途径

    Tube Formation
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