DVL1 抗体 (C-Term)
Quick Overview for DVL1 抗体 (C-Term) (ABIN2779457)
抗原
See all DVL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- AAGAGGSGSE SDHTAPSGVG SSWRERPAGQ LSRGSSPRSQ ASATAPGLPP
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预测反应
- Cow: 86%, Dog: 86%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 93%, Rat: 86%, Yeast: 85%
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产品特性
- This is a rabbit polyclonal antibody against DVL1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human DVL1
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anti-Dishevelled Segment Polarity Protein 1 (DVL1) (AA 21-100) antibody
DVL1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Dishevelled Segment Polarity Protein 1 (DVL1) (AA 442-470) antibodyDVL1 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB31716 unconjugated
anti-Dishevelled Segment Polarity Protein 1 (DVL1) (AA 150-285) antibodyDVL1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dishevelled Segment Polarity Protein 1 (DVL1) (AA 20-32) antibodyVerified DVL1 适用: 人 IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Dishevelled Segment Polarity Protein 1 (DVL1) (AA 510-640) antibodyDVL1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dishevelled Segment Polarity Protein 1 (DVL1) (AA 1-110) antibodyDVL1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Dishevelled Segment Polarity Protein 1 (DVL1) (Internal Region) antibodyVerified DVL1 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Dishevelled Segment Polarity Protein 1 (DVL1) (AA 1-444) antibodyDVL1 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Dishevelled Segment Polarity Protein 1 (DVL1) (AA 569-618) antibodyDVL1 适用: 人, 小鼠, 大鼠, Cow, 犬, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Dishevelled Segment Polarity Protein 1 (DVL1) (AA 412-461) antibodyDVL1 适用: 人, Pig, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 670 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- DVL1 (Dishevelled Segment Polarity Protein 1 (DVL1))
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别名
- DVL1
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背景
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DVL1 is a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 gene is a candidate for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1 gene. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development. Three transcript variants encoding three different isoforms have been found for this gene.
Alias Symbols: DVL, MGC54245, DVL1L1
Protein Interaction Partner: NCK2, TRIM69, NUMA1, HUWE1, UBC, DVL2, WWOX, SIPA1, PSMA3, LRRK2, ITCH, HECW1, NEDD4, ANXA7, SDC4, NKD2, CYLD, SIRT1, CCDC88C, VANGL1, CXXC4, PPM1A, DYNLT1, HDHD2, BRD7, DAAM1, AXIN1, USP13, SMAD3, SMAD7, FRAT1, RAC1, DVL3, SMAD2, DVL1, SMAD4, CSNK1D, CSN
Protein Size: 670 -
分子量
- 73 kDa
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基因ID
- 1855
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NCBI登录号
- NM_004421, NP_004412
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途径
- WNT signaling, Synaptic Membrane, Skeletal Muscle Fiber Development
抗原
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