DVL1 抗体 (Middle Region)
Quick Overview for DVL1 抗体 (Middle Region) (ABIN2779456)
抗原
See all DVL1 抗体适用
宿主
克隆类型
标记
应用范围
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                                            抗原表位
- Middle Region
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                                            序列
- LKITIANAVI GADVVDWLYT HVEGFKERRE ARKYASSLLK HGFLRHTVNK
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                                            预测反应
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 87%
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                                            产品特性
- This is a rabbit polyclonal antibody against DVL1. It was validated on Western Blot.
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                                            纯化方法
- Protein A purified
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                                            免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human DVL1
 
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                                            应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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                                            说明
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                        Antigen size: 353 AA 
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                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Liquid
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                                            浓度
- Lot specific
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                                            缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            注意事项
- Avoid repeated freeze-thaw cycles.
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                                            储存条件
- -20 °C
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                                            储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
 
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    - DVL1 (Dishevelled Segment Polarity Protein 1 (DVL1))
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                                            别名
- DVL1
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                                            背景
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                        DVL1 is a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 gene is a candidate for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1 gene. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.
 Alias Symbols: DVL, MGC54245, DVL1L1
 Protein Interaction Partner: NCK2, TRIM69, NUMA1, HUWE1, UBC, DVL2, WWOX, SIPA1, PSMA3, LRRK2, ITCH, HECW1, NEDD4, ANXA7, SDC4, NKD2, CYLD, SIRT1, CCDC88C, VANGL1, CXXC4, PPM1A, DYNLT1, HDHD2, BRD7, DAAM1, AXIN1, USP13, SMAD3, SMAD7, FRAT1, RAC1, DVL3, SMAD2, DVL1, SMAD4, CSNK1D, CSN
 Protein Size: 353
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                                            分子量
- 38 kDa
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                                            基因ID
- 1855
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                                            NCBI登录号
- NM_004421
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                                            UniProt
- A6NKG8
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                                            途径
- WNT signaling, Synaptic Membrane, Skeletal Muscle Fiber Development
 抗原
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