PAWR 抗体 (Middle Region)
Quick Overview for PAWR 抗体 (Middle Region) (ABIN2779443)
抗原
See all PAWR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- VNIPAAECLD EYEDDEAGQK ERKREDAITQ QNTIQNEAVN LLDPGSSYLL
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预测反应
- Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against PAWR. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human PAWR
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 340 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PAWR (PRKC, Apoptosis, WT1, Regulator (PAWR))
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别名
- PAWR
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背景
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The tumor suppressor WT1 represses and activates transcription. Anti-Prostate Apoptosis Response Protein Par-4 (PAWR) is a WT1-interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc finger DNA binding domain of WT1. This protein is specifically upregulated during apoptosis of prostate cells.
Alias Symbols: PAR4, Par-4
Protein Interaction Partner: FBXO45, UBC, EED, FAM129B, SNX6, CAND1, VPS29, JMJD6, STAT1, SNX2, SHMT2, SHMT1, PPM1G, IDE, H3F3A, CARS, ATP6V1C1, APEH, PAN2, DRD2, DAPK3, SQSTM1, PRKCZ, Spsb4, Spsb2, SPSB1, FBXO25, HSPA5, Cep350, Kif23, THAP1, SLC5A7, AATF, TFPT, PAWR, WT1, RRAS2, ATP
Protein Size: 340 -
分子量
- 37 kDa
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基因ID
- 5074
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NCBI登录号
- NM_002583, NP_002574
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UniProt
- O75796
抗原
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