NKX3-1 抗体 (Middle Region)
Quick Overview for NKX3-1 抗体 (Middle Region) (ABIN2779438)
抗原
See all NKX3-1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Middle Region
-
序列
- KRKQLSSELG DLEKHSSLPA LKEEAFSRAS LVSVYNSYPY YPYLYCVGSW
-
预测反应
- Cow: 79%, Dog: 86%, Guinea Pig: 85%, Horse: 79%, Human: 100%, Rabbit: 79%, Rat: 93%
-
产品特性
- This is a rabbit polyclonal antibody against NKX3-1. It was validated on Western Blot using a cell lysate as a positive control.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human NKX3-1
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 234 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- NKX3-1 (NK3 Homeobox 1 (NKX3-1))
-
别名
- NKX3-1
-
背景
-
The homeodomain-containing transcription factor NKX3-1 is a putative prostate tumor suppressor that is expressed in a largely prostate-specific and androgen-regulated manner. Loss of NKX3-1 protein expression is a common finding in human prostate carcinomas and prostatic intraepithelial neoplasia.The homeodomain-containing transcription factor NKX3A is a putative prostate tumor suppressor that is expressed in a largely prostate-specific and androgen-regulated manner. Loss of NKX3A protein expression is a common finding in human prostate carcinomas and prostatic intraepithelial neoplasia.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: BAPX2, NKX3, NKX3.1, NKX3A
Protein Interaction Partner: STRA13, CHPF, AEN, RABL6, TEX264, STMN3, LMCD1, SPDEF, CKAP4, HNRNPA0, CCT7, HMG20B, FEM1B, HSP90B1, TPT1, RPL37A, RARG, PTMS, PEBP1, ND4, MNAT1, MAN2B1, RPSA, TOP1, WDR77, TOPORS, KAT2B, SP5, SP4, SP3, SP2, SP1, HDAC1, HIPK2, SRF,
Protein Size: 234 -
分子量
- 26 kDa
-
基因ID
- 4824
-
NCBI登录号
- NM_006167, NP_006158
-
UniProt
- Q99801
-
途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Endopeptidase Activity, Positive Regulation of Response to DNA Damage Stimulus
抗原
-