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IRF3 抗体 (C-Term)

This 兔多克隆 antibody specifically detects IRF3 in WB. It exhibits reactivity toward 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 绵羊和马.

Rabbit Anti-IRF3 Antibody Formalin Fixed Paraffin Embedded Tissue: Human Lymph Node Tissue Observed Staining: Cytoplasm Primary Antibody Concentration: 1:100 Other Working Concentrations: 1:600 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0. (IRF3 抗体 (C-Term))

IHC

2 images

产品编号 ABIN2779404

发货至: 中国

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Quick Overview for IRF3 抗体 (C-Term) (ABIN2779404)

抗原

See all IRF3 抗体

IRF3 (Interferon Regulatory Factor 3 (IRF3))

适用

人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 绵羊, 马

宿主

兔

克隆类型

多克隆

标记

This IRF3 antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product IRF3 Primary Antibody

抗原表位
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C-Term

序列

SWPQDQPWTK RLVMVKVVPT CLRALVEMAR VGGASSLENT VDLHISNSHP

预测反应

Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 100%, Sheep: 100%

产品特性

This is a rabbit polyclonal antibody against IRF3. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the C terminal region of human IRF3
anti-Interferon Regulatory Factor 3 (IRF3) (pSer396) antibody
IRF3 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Interferon Regulatory Factor 3 (IRF3) (AA 1-260) antibody
IRF3 适用: 人 WB, IHC, IF, ChIP 宿主: 兔 Polyclonal unconjugated

anti-Interferon Regulatory Factor 3 (IRF3) (AA 1-452) antibody
IRF3 适用: 人 WB, ELISA, IF, IP 宿主: 小鼠 Monoclonal 3C8 unconjugated

anti-Interferon Regulatory Factor 3 (IRF3) (AA 51-150) antibody
IRF3 适用: 人, 小鼠, 大鼠, 猴, Cow WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Interferon Regulatory Factor 3 (IRF3) (AA 1-360) antibody
IRF3 适用: 人 WB, IHC, ICC, IP, FACS 宿主: 兔 Polyclonal unconjugated

anti-Interferon Regulatory Factor 3 (IRF3) (pSer386) antibody
IRF3 适用: 人, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Interferon Regulatory Factor 3 (IRF3) (C-Term) antibody
IRF3 适用: 人 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Interferon Regulatory Factor 3 (IRF3) antibody
IRF3 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF (cc) 宿主: 兔 Monoclonal 4C3 unconjugated

anti-Interferon Regulatory Factor 3 (IRF3) antibody
IRF3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Interferon Regulatory Factor 3 (IRF3) (AA 1-452) antibody
IRF3 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 427 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
抗原

IRF3 (Interferon Regulatory Factor 3 (IRF3))

别名

IRF3

背景

IRF3 is interferon regulatory factor 3, a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes.IRF3 encodes interferon regulatory factor 3, a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes.IRF3 encodes interferon regulatory factor 3, a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes.
Protein Interaction Partner: IRF3, UBC, TMEM173, POLR2A, DEAF1, CREBBP, MAFB, vIRF-3, SMAD4, SMAD2, FOXO1, vIRF-1, EP300, SGTA, PEX19, HSP90AA1, PIAS4, TBK1, TOMM70A, TLR2, MAPK9, MAPK8, MAVS, DDX58, TRAF3, ISG15, TRIM21, PIN1, IRF7, HERC5, IKBKE, CUL1, SUMO2, XIAP, HDAC3, SOCS1, RBL
Protein Size: 427

分子量

47 kDa

基因ID

3661

NCBI登录号

NM_001571, NP_001562

UniProt

Q14653

途径

TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades