RAD17 抗体 (N-Term)
Quick Overview for RAD17 抗体 (N-Term) (ABIN2779342)
抗原
See all RAD17 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- MNQVTDWVDP SFDDFLECSG VSTITATSLG VNNSSHRRKN GPSTLESSRF
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预测反应
- Cow: 89%, Dog: 100%, Horse: 92%, Human: 100%, Pig: 100%, Rabbit: 100%, Rat: 89%
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产品特性
- This is a rabbit polyclonal antibody against RAD17. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human RAD17
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 670 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- RAD17
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别名
- RAD17
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背景
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RAD17 is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by ATR after the damage. This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, which may be required for its phosphorylation.
Alias Symbols: CCYC, FLJ41520, HRAD17, R24L, RAD17SP, RAD24
Protein Interaction Partner: USP20, UBC, PRMT6, CBX7, CBX6, RAD9A, CDH1, ATR, RFC1, H2AFX, FOXO3, ATM, CLSPN, ALK, RAD9B, POLE, HUS1, RAD1, NHP2L1, MCM7, RFC4, RFC5, RFC3, RFC2, POLE4, POLE3, POLE2, PRKDC,
Protein Size: 670 -
分子量
- 76 kDa
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基因ID
- 5884
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NCBI登录号
- NM_002873, NP_002864
抗原
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