ILK 抗体 (C-Term)
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北京 101111
Quick Overview for ILK 抗体 (C-Term) (ABIN2779334)
抗原
See all ILK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- MKVALEGLRP TIPPGISPHV CKLMKICMNE DPAKRPKFDM IVPILEKMQD
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预测反应
- Cow: 100%, Dog: 100%, Goat: 82%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against ILK. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human ILK
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ILK (Integrin-Linked Kinase (ILK))
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别名
- ILK
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背景
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Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. This gene encodes a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
Alias Symbols: ILK-2, P59
Protein Interaction Partner: UBC, TRIM27, PARVG, PARVA, RICTOR, ITGB1, MTOR, AKT1, FKBP5, HSPH1, FAF1, CARM1, UGP2, PPAT, FBXO6, ACACA, LIMS2, RHOT1, FANCI, ATAD3A, HEATR1, CLN6, TRAFD1, ZNF568, TIMM50, RHOT2, TRABD, LPCAT1, VKORC1, RPL13, ABCE1, RBBP7, RAF1, SDF4, SEC61A1, PARVB, AK
Protein Size: 452 -
分子量
- 49 kDa
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基因ID
- 3611
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NCBI登录号
- NM_004517, NP_004508
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UniProt
- Q13418
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途径
- Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Smooth Muscle Cell Migration
抗原
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