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c-MYC 抗体 (N-Term)

There is 1 publication for this product available. The 兔多克隆 anti-c-MYC antibody is suitable to detect c-MYC in samples from 人, 小鼠, 大鼠, 犬, Cow, 绵羊, 兔, 斑马鱼, 豚鼠和马. It has been validated for WB.

Rabbit Anti-MYC Antibody Catalog Number: ARP30292_P050 Formalin Fixed Paraffin Embedded Tissue: Human Lymph Node Tissue Observed Staining: Nucleus Primary Antibody Concentration: 1:100 Other Working Concentrations: N/A Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0. (c-MYC 抗体 (N-Term))

IHC

2 images

(1 reference)

产品编号 ABIN2779313

发货至: 中国

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Quick Overview for c-MYC 抗体 (N-Term) (ABIN2779313)

抗原

See all c-MYC (MYC) 抗体

c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

适用

人, 小鼠, 大鼠, 犬, Cow, 绵羊, 兔, 斑马鱼, 豚鼠, 马

宿主

兔

克隆类型

多克隆

标记

This c-MYC antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product MYC Primary Antibody

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N-Term

原理

MYC Antibody - N-terminal region

序列

QPYFYCDEEE NFYQQQQQSE LQPPAPSEDI WKKFELLPTP PLSPSRRSGL

预测反应

Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

产品特性

This is a rabbit polyclonal antibody against MYC. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human MYC
anti-Myc Proto-Oncogene protein (MYC) (Center) antibody
MYC 适用: 人, 小鼠 WB, IF, IP, ICC, ChIP 宿主: 兔 Polyclonal unconjugated

anti-Myc Proto-Oncogene protein (MYC) (AA 330-439) antibody
MYC 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1G7 unconjugated

anti-Myc Proto-Oncogene protein (MYC) (AA 31-80) antibody
MYC 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Myc Proto-Oncogene protein (MYC) (AA 360-440) antibody
MYC 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Myc Proto-Oncogene protein (MYC) (AA 257-439) antibody
MYC 适用: 人, 小鼠, 大鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Myc Proto-Oncogene protein (MYC) (AA 101-200) antibody
MYC 适用: 人 WB, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated

anti-Myc Proto-Oncogene protein (MYC) antibody
MYC 适用: 人 ELISA 宿主: 小鼠 Monoclonal 7E10 unconjugated

anti-Myc Proto-Oncogene protein (MYC) (pThr58) antibody
MYC 适用: 人 WB, DB 宿主: 兔 Polyclonal RB11187 unconjugated

anti-Myc Proto-Oncogene protein (MYC) (AA 408-439) antibody
MYC 适用: 人 WB, IHC, IF, FACS, ELISA, IP, IHC (p) 宿主: 小鼠 Monoclonal 9E10 unconjugated

anti-Myc Proto-Oncogene protein (MYC) (N-Term) antibody
MYC 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

说明

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP30292-100UG

限制

仅限研究用
状态

Liquid

浓度

0.5 mg/mL

缓冲液

Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

prevent freeze-thaw cycles

储存条件

4 °C,-20 °C

储存方法

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Mallampalli, Kaercher, Snavely, Pulijala, Chen, Coon, Zhao, Agassandian: "Fbxl12 triggers G1 arrest by mediating degradation of calmodulin kinase I." in: Cellular signalling, Vol. 25, Issue 10, pp. 2047-59, (2013) (PubMed).
抗原

c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

别名

MYC

背景

Background Information: MYC is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this MYC gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma.The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Gene Name: V-myc myelocytomatosis viral oncogene homolog (avian)
Alternative Symbols: MRTL, MYCC, c-Myc, bHLHe39
Protein Name: Myc proto-oncogene protein

分子量

50kDa

基因ID

4609

NCBI登录号

NP_002458

UniProt

P01106

途径

p53 Pathway, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effect