Amphiregulin 抗体 (Middle Region)
Quick Overview for Amphiregulin 抗体 (Middle Region) (ABIN2779308)
抗原
See all Amphiregulin (AREG) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- PQIPGYIVDD SVRVEQVVKP PQNKTESENT SDKPKRKKKG GKNGKNRRNR
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预测反应
- Cow: 91%, Dog: 91%, Horse: 91%, Human: 100%, Pig: 91%, Sheep: 91%
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产品特性
- This is a rabbit polyclonal antibody against AREG. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human AREG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 252 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Amphiregulin (AREG)
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别名
- AREG
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背景
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The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells, and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). This protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells and inhibits the growth of certain aggressive carcinoma cell lines. This encoded protein is associated with a psoriasis-like skin phenotype.
Alias Symbols: AR, AREGB, CRDGF, MGC13647, SDGF
Protein Interaction Partner: KRTAP10-3, WDR92, UBC, APP, UBQLN4, WT1, EGFR, CCND3, MMP9,
Protein Size: 252 -
分子量
- 28 kDa
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基因ID
- 374
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NCBI登录号
- NM_001657, NP_001648
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UniProt
- P15514
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途径
- RTK signaling, EGFR Signaling Pathway
抗原
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