RENT2/UPF2 抗体 (N-Term)
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北京 101111
Quick Overview for RENT2/UPF2 抗体 (N-Term) (ABIN2779085)
抗原
See all RENT2/UPF2 (UPF2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- UPF2 Antibody - N-terminal region
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序列
- KAPEDKKKRL EDDKRKKEDK ERKKKDEEKV KAEEESKKKE EEEKKKHQEE
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预测反应
- Cow: 93%, Dog: 93%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 93%, Rat: 86%, Yeast: 86%, Zebrafish: 86%
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产品特性
- This is a rabbit polyclonal antibody against UPF2. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human UPF2
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP40814-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- RENT2/UPF2 (UPF2) (UPF2 Regulator of Nonsense Transcripts 2 (UPF2))
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别名
- UPF2
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背景
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Background Information: This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p. Two splice variants have been found for this gene, both variants encode the same protein.
Gene Name: UPF2 regulator of nonsense transcripts homolog (yeast)
Alternative Symbols: HUPF2, RENT2, smg-3
Protein Name: Regulator of nonsense transcripts 2
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分子量
- 148kDa
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基因ID
- 26019
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NCBI登录号
- NP_056357
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UniProt
- Q9HAU5
抗原
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