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NONO 抗体 (N-Term)

Name: NONO 抗体 (N-Term)
SKU: ABIN2779027
Availability: OutOfStock

Cited in 2+ publications. This 兔多克隆 anti-NONO antibody specifically detects NONO in WB 和 IF. The antibody is reactive with 人, 小鼠, 大鼠, 犬, 马, Cow 和豚鼠 samples.

WB Suggested Anti-NONO Antibody Titration: 1. (NONO 抗体 (N-Term))

Image no. 2 for anti-Non-POU Domain Containing, Octamer-Binding (NONO) (N-Term) antibody (ABIN2779027) (NONO 抗体 (N-Term))

Sample Type: subnuclear bodies-paraspeckles (NONO 抗体 (N-Term))

3 images

(2 references)

产品编号 ABIN2779027

发货至: 中国

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Quick Overview for NONO 抗体 (N-Term) (ABIN2779027)

抗原

See all NONO 抗体

NONO (Non-POU Domain Containing, Octamer-Binding (NONO))

适用

人, 小鼠, 大鼠, 犬, 马, Cow, 豚鼠

宿主

兔

克隆类型

多克隆

标记

This NONO antibody is un-conjugated

应用范围

Western Blotting (WB), Immunofluorescence (IF)

Discover our top product NONO Primary Antibody

抗原表位
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1

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1

1

1

1
N-Term

序列

KQNHTPRKHH QHHHQQQHHQ QQQQQPPPPP IPANGQQASS QNEGLTIDLK

预测反应

Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%

产品特性

This is a rabbit polyclonal antibody against NONO. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Protein A purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human NONO
anti-Non-POU Domain Containing, Octamer-Binding (NONO) (AA 1-300) antibody
NONO 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Non-POU Domain Containing, Octamer-Binding (NONO) (AA 184-385) antibody
NONO 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2E7 unconjugated

anti-Non-POU Domain Containing, Octamer-Binding (NONO) (AA 184-385) antibody
NONO 适用: 人, 小鼠, 犬, 猴 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 3F8 unconjugated

anti-Non-POU Domain Containing, Octamer-Binding (NONO) (C-Term) antibody
NONO 适用: 人, 小鼠, 大鼠, 犬, 马, Cow, 豚鼠, 兔 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Non-POU Domain Containing, Octamer-Binding (NONO) antibody
NONO 适用: 人 WB, IHC, IF, ELISA 宿主: 兔 Monoclonal 8C11 unconjugated Recombinant Antibody

anti-Non-POU Domain Containing, Octamer-Binding (NONO) (N-Term) antibody
NONO 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-Non-POU Domain Containing, Octamer-Binding (NONO) (C-Term) antibody
NONO 适用: 人, 犬, 猴, 马, Cow, 豚鼠, 兔, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Non-POU Domain Containing, Octamer-Binding (NONO) (C-Term) antibody
NONO 适用: 人, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Non-POU Domain Containing, Octamer-Binding (NONO) (AA 1-35), (N-Term) antibody
NONO 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Non-POU Domain Containing, Octamer-Binding (NONO) (AA 1-300) antibody
NONO 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 471 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bubenik, Ladd, Gerber, Budiman, Driscoll: "Known turnover and translation regulatory RNA-binding proteins interact with the 3' UTR of SECIS-binding protein 2." in: RNA biology, Vol. 6, Issue 1, pp. 73-83, (2009) (PubMed).

Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).
抗原

NONO (Non-POU Domain Containing, Octamer-Binding (NONO))

别名

NONO

背景

NONO is DNA- and RNA binding protein, involved in several nuclear processes. It binds the conventional octamer sequence in double stranded DNA. It also binds single-stranded DNA and RNA at a site independent of the duplex site. It is involved in pre-mRNA splicing and interacts with U5 snRNA. The SFPQ-NONO heteromer associated with MATR3 may play a role in nuclear retention of defective RNAs, be involved in DNA unwinding by modulating the function of topoisomerase I/TOP1 and be involved in DNA nonhomologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination and may stabilize paired DNA ends. NONO binds to an enhancer element in long terminal repeats of endogenous intracisternal A particles (IAPs) and activates transcription.
Alias Symbols: P54, NMT55, NRB54, P54NRB
Protein Interaction Partner: SFPQ, PTBP1, PRKAA2, PIN1, NONO, FUS, DDX6, C11orf68, PSPC1, HUWE1, LMO4, UBC, SUMO2, STAU1, MDM2, RPA3, RPA2, RPA1, ASB18, WWOX, ASB3, ERG, EED, rev, WBP4, TCERG1, APBB1, PRPF40A, LMNA, CD81, PAN2, CTNNB1, ORC5, MYC, ITGA4, IL7R, FN1, EWSR1, YLPM1, RNF43
Protein Size: 471

分子量

52 kDa

基因ID

4841

NCBI登录号

NM_007363, NP_031389

UniProt

Q15233