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CELF2 抗体 (N-Term)

Cited in 1 publication. The 兔 多克隆 anti-CELF2 antibody (ABIN2779001) specifically detects CELF2 in WB 和 IHC. The antibody is reactive with 人 和 Cow samples.
产品编号 ABIN2779001
发货至: 中国
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Quick Overview for CELF2 抗体 (N-Term) (ABIN2779001)

抗原

See all CELF2 抗体
CELF2 (CUGBP, Elav-Like Family Member 2 (CELF2))

适用

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  • 18
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人, Cow

宿主

  • 45
  • 2

克隆类型

  • 35
  • 12
多克隆

标记

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  • 3
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This CELF2 antibody is un-conjugated

应用范围

  • 34
  • 17
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  • 4
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  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 8
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    序列

    TSAFKLDFLP DMMVEGRLLV PDRINGTANK MNGALDHSDQ PDPDAIKMFV

    预测反应

    Cow: 100%, Human: 100%

    产品特性

    This is a rabbit polyclonal antibody against CUGBP2. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human CUGBP2
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 521 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Subramaniam, Natarajan, Ramalingam, Ramachandran, May, Queimado, Houchen, Anant: "Translation inhibition during cell cycle arrest and apoptosis: Mcl-1 is a novel target for RNA binding protein CUGBP2." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 294, Issue 4, pp. G1025-32, (2008) (PubMed).

  • 抗原

    CELF2 (CUGBP, Elav-Like Family Member 2 (CELF2))

    别名

    CUGBP2

    背景

    CUGBP2 is a member of the CELF/BRUNOL protein family, which contains two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of CUGBP2 family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. If alternative splicing were to result, multiple transcript variants encoding different isoforms would appear.Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Alternative splicing results in multiple transcript variants encoding different isoforms.
    Alias Symbols: BRUNOL3, ETR-3, NAPOR, ETR3, CUGBP2
    Protein Interaction Partner: PTGS2, ELAVL1, UBC, FN1, APP, PCBP1, A1CF, APOBEC1, Apob,
    Protein Size: 521

    分子量

    56 kDa

    基因ID

    10659

    NCBI登录号

    NM_006561, NP_006552

    途径

    Ribonucleoprotein Complex Subunit Organization
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