NXF1 抗体 (N-Term)
Quick Overview for NXF1 抗体 (N-Term) (ABIN2778976)
抗原
See all NXF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- RPNRRGDTWH DRDRIHVTVR RDRAPPERGG AGTSQDGTSK NWFKITIPYG
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against NXF1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human NXF1
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anti-Nuclear RNA Export Factor 1 (NXF1) (N-Term) antibody
NXF1 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear RNA Export Factor 1 (NXF1) (N-Term) antibodyNXF1 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear RNA Export Factor 1 (NXF1) (C-Term) antibodyNXF1 适用: 人 WB, IP, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear RNA Export Factor 1 (NXF1) antibodyNXF1 适用: 人, 小鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear RNA Export Factor 1 (NXF1) (N-Term) antibodyNXF1 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, Cow WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear RNA Export Factor 1 (NXF1) (N-Term) antibodyNXF1 适用: 人, 犬, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear RNA Export Factor 1 (NXF1) (N-Term) antibodyNXF1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Nuclear RNA Export Factor 1 (NXF1) (AA 1-130) antibodyNXF1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear RNA Export Factor 1 (NXF1) (AA 78-127) antibodyNXF1 适用: 人, 犬, 豚鼠, Cow, 猴, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Nuclear RNA Export Factor 1 (NXF1) (AA 57-356) antibodyNXF1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 619 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- NXF1 (Nuclear RNA Export Factor 1 (NXF1))
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别名
- NXF1
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背景
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NXF1 is one member of a family of nuclear RNA export factor. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. NXF1 shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. NXF1 overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses.This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. It is the vertebrate homologue of the yeast protein Mex67p. The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses.This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. It is the vertebrate homologue of the yeast protein Mex67p. The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses.
Alias Symbols: DKFZp667O0311, MEX67, TAP
Protein Interaction Partner: KRT40, TIFA, GFAP, LDOC1, NUP62, MID2, TP53BP2, DVL3, SUMO2, UBC, SUZ12, EED, BMI1, TARDBP, NXT1, NUP98, RANBP2, ESRRA, KCTD5, TRA2A, SGTA, TRA2B, SRSF1, RAD51, ZBED2, CSNK2A1, EIF2A, ILF3, HNRNPC, HNRNPK, DHX15, DHX9, DDB1, DDX19A, LUC7L3, HP1BP3, RBMX,
Protein Size: 619 -
分子量
- 68 kDa
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基因ID
- 10482
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NCBI登录号
- NM_006362, NP_006353
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UniProt
- Q9UBU9
抗原
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