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HNRNPM 抗体 (N-Term)

This anti-HNRNPM antibody is a 兔 多克隆 antibody detecting HNRNPM in WB. Suitable for 人, 小鼠, 大鼠, Cow, Pig, 犬, 马, 兔 和 豚鼠. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN2778962
发货至: 中国

Quick Overview for HNRNPM 抗体 (N-Term) (ABIN2778962)

抗原

See all HNRNPM 抗体
HNRNPM (Heterogeneous Nuclear Ribonucleoprotein M (HNRNPM))

适用

人, 小鼠, 大鼠, Cow, Pig, 犬, 马, 兔, 豚鼠

宿主

  • 46
  • 8

克隆类型

  • 44
  • 10
多克隆

标记

  • 28
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This HNRNPM antibody is un-conjugated

应用范围

  • 31
  • 25
  • 21
  • 14
  • 13
  • 13
  • 13
  • 6
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB)
  • 抗原表位

    • 15
    • 8
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    序列

    ATEIKMEEES GAPGVPSGNG APGPKGEGER PAQNEKRKEK NIKRGGNRFE

    预测反应

    Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 92%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 93%, Rat: 93%

    产品特性

    This is a rabbit polyclonal antibody against HNRPM. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human HNRPM
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 691 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Huelga, Vu, Arnold, Liang, Liu, Yan, Donohue, Shiue, Hoon, Brenner, Ares, Yeo: "Integrative genome-wide analysis reveals cooperative regulation of alternative splicing by hnRNP proteins." in: Cell reports, Vol. 1, Issue 2, pp. 167-78, (2012) (PubMed).

    Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

  • 抗原

    HNRNPM (Heterogeneous Nuclear Ribonucleoprotein M (HNRNPM))

    别名

    HNRPM

    背景

    HNRPM belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. HNRPM has three repeats of quasi-RRM domains that bind to RNAs. HNRPM also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules.This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Multiple alternatively spliced transcript variants are known for this gene but only two transcripts has been isolated.
    Alias Symbols: DKFZp547H118, HNRNPM, HNRNPM4, HNRPM4, HTGR1, NAGR1, CEAR, HNRPM, hnRNP M
    Protein Interaction Partner: UBC, TP53, AKAP9, TEKT4, GMCL1P1, LMO2, HNRNPF, SUMO2, SUMO3, CEP250, MDM2, HAUS1, CDC37, IVNS1ABP, STAU1, SUMO1, RPA3, RPA2, RPA1, EED, rev, RTCB, RPL26L1, RFC4, PSMB8, NMT1, MRE11A, FLII, IGF2BP3, EIF2B2, EIF2B3, RPL27, RPL19, DHX9, DDX1, ABCF1, PARK2,
    Protein Size: 691

    分子量

    73 kDa

    基因ID

    4670

    NCBI登录号

    NM_031203, NP_112480

    UniProt

    P52272
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