SMNDC1 抗体 (Middle Region)
Quick Overview for SMNDC1 抗体 (Middle Region) (ABIN2778955)
抗原
See all SMNDC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- QFNNRAYSKN KKGQVKRSIF ASPESVTGKV GVGTCGIADK PMTQYQDTSK
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预测反应
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against SMNDC1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human SMNDC1
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 238 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SMNDC1 (Survival Motor Neuron Domain Containing 1 (SMNDC1))
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别名
- SMNDC1
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背景
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This gene is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. SMNDC1 is a nuclear protein that has been identified as a constituent of the spliceosome complex. This gene is differentially expressed, with abundant levels in skeletal muscle, and may share similar cellular function as the SMN1 gene. This gene is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. The protein encoded by this gene is a nuclear protein that has been identified as a constituent of the spliceosome complex. This gene is differentially expressed, with abundant levels in skeletal muscle, and may share similar cellular function as the SMN1 gene.
Alias Symbols: SMNR, SPF30
Protein Interaction Partner: UBC, PRPF3, SF3B5, SND1, CUL3, SF3A2, ELAVL1, HIST3H3, mad2, KPNB1, SNRNP200, SNRPB, CDK5RAP3, PPAN, TSR1, RNMTL1, SF3B1, SF3B3, SF3B2, SF3A3, SF3B4, DDX21, RUVBL1, RPL3, FDFT1, EWSR1,
Protein Size: 238 -
分子量
- 27 kDa
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基因ID
- 10285
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NCBI登录号
- NM_005871, NP_005862
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UniProt
- O75940
抗原
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