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RBM8A 抗体 (N-Term)

This anti-RBM8A antibody is a 兔 多克隆 antibody detecting RBM8A in WB. Suitable for 人, 大鼠, 小鼠, 斑马鱼, Cow, 犬, 马, 兔 和 豚鼠.
产品编号 ABIN2778928
发货至: 中国

Quick Overview for RBM8A 抗体 (N-Term) (ABIN2778928)

抗原

See all RBM8A 抗体
RBM8A (RNA Binding Motif Protein 8A (RBM8A))

适用

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人, 大鼠, 小鼠, 斑马鱼, Cow, 犬, 马, 兔, 豚鼠

宿主

  • 37
  • 5

克隆类型

  • 36
  • 7
多克隆

标记

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This RBM8A antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

    • 6
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    N-Term

    序列

    EDFAMDEDGD ESIHKLKEKA KKRKGRGFGS EEGSRARMRE DYDSVEQDGD

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against Rbm8a. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N-terminal region of Rat Rbm8a
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 174 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    RBM8A (RNA Binding Motif Protein 8A (RBM8A))

    别名

    Rbm8a

    背景

    Rbm8a is a component of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Core components of the EJC, that remains bound to spliced mRNAs throughout all stages of mRNA metabolism, functions to mark the position of the exon-exon junction in the mature mRNA and thereby influences downstream processes of gene expression including mRNA splicing, nuclear mRNA export, subcellular mRNA localization, translation efficiency and nonsense-mediated mRNA decay (NMD). The heterodimer MAGOH-RBM8A interacts with PYM that function to enhance the translation of EJC-bearing spliced mRNAs by recruiting them to the ribosomal 48S preinitiation complex.
    Alias Symbols: Rbm8
    Protein Interaction Partner: Stau2,
    Protein Size: 174

    分子量

    19 kDa

    基因ID

    295284

    NCBI登录号

    XM_215637, XP_215637

    UniProt

    Q27W01
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