PABPC4 抗体 (N-Term)
Quick Overview for PABPC4 抗体 (N-Term) (ABIN2778874)
抗原
See all PABPC4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- AELGAKAKEF TNVYIKNFGE EVDDESLKEL FSQFGKTLSV KVMRDPNGKS
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预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%
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产品特性
- This is a rabbit polyclonal antibody against PABPC4. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human PABPC4
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anti-Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4) (AA 350-450) antibody
PABPC4 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4) (Internal Region) antibodyPABPC4 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IP 宿主: 兔 Polyclonal unconjugated
anti-Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4) (AA 181-230) antibodyPABPC4 适用: 人, 小鼠, 大鼠, 犬, 马, 猴, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4) (AA 18-229) antibodyPABPC4 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4) (N-Term) antibodyPABPC4 适用: 人, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4) (AA 1-660) antibodyPABPC4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4) (AA 432-481) antibodyPABPC4 适用: 人, 大鼠, 豚鼠, 马, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4) (Middle Region) antibodyPABPC4 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, Cow, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 644 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PABPC4 (Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4))
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别名
- PABPC4
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背景
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Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules.Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules.
Alias Symbols: APP1, APP-1, PABP4, iPABP
Protein Interaction Partner: FBXW11, UBC, IVNS1ABP, STAU1, RPA3, RPA2, RPA1, WWOX, SUZ12, RNF2, EZH2, BMI1, NCAPD2, DDX5, TARDBP, SRPK2, CLK3, YWHAQ, UBD, EIF2AK2, PAN2, UBL4A, SMAD9, ITGA4, IL7R, IFIT3, IFIT1, IFIT2, FN1, IGBP1, NUBP2, CAND1, DCUN1D1, COPS5, CUL1, CUL2, CUL3, CUL4A,
Protein Size: 644 -
分子量
- 71 kDa
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基因ID
- 8761
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NCBI登录号
- NM_003819, NP_003810
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UniProt
- Q13310
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途径
- SARS-CoV-2 Protein Interactome
抗原
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