XPO1 抗体 (Middle Region)
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北京 101111
Quick Overview for XPO1 抗体 (Middle Region) (ABIN2778850)
抗原
See all XPO1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- XPO1 Antibody - middle region
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序列
- IPAFKEHLRD FLVQIKEFAG EDTSDLFLEE REIALRQADE EKHKRQMSVP
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预测反应
- Cow: 86%, Dog: 86%, Guinea Pig: 77%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 86%, Rat: 86%, Zebrafish: 79%
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产品特性
- This is a rabbit polyclonal antibody against XPO1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human XPO1
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP40466-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- XPO1 (Exportin 1 (XPO1))
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别名
- XPO1
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背景
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Background Information: XPO1 mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is also involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1.The protein encoded by this gene mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Gene Name: Exportin 1 (CRM1 homolog, yeast)
Alternative Symbols: emb, CRM1, exp1, CRM-1
Protein Name: Exportin-1
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分子量
- 123kDa
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基因ID
- 7514
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NCBI登录号
- NP_003391
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UniProt
- O14980
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途径
- M Phase
抗原
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