NCBP1 抗体 (N-Term)
Quick Overview for NCBP1 抗体 (N-Term) (ABIN2778796)
抗原
See all NCBP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- SRRRHSDEND GGQPHKRRKT SDANETEDHL ESLICKVGEK SACSLESNLE
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预测反应
- Cow: 100%, Dog: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 88%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against NCBP1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human NCBP1
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 790 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- NCBP1 (Nuclear Cap Binding Protein Subunit 1, 80kDa (NCBP1))
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别名
- NCBP1
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背景
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NCBP1 is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay.The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CBP80, MGC2087, NCBP, Sto1
Protein Interaction Partner: POLDIP3, HUWE1, EIF4G1, UPF3B, EIF3B, MTOR, RPS6KB1, ALYREF, DDX39B, THOC3, THOC2, IVNS1ABP, UBC, LIN28B, LIN28A, ZNF346, SUMO1, SUZ12, EED, RNF2, BMI1, VAT1, MVP, TTC1, PPM1G, SERPINE2, NCL, NAP1L4, GFPT1, GARS, PUS1, TARDBP, YWHAE, RUVBL1, MPG, FN1, C17
Protein Size: 790 -
分子量
- 92 kDa
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基因ID
- 4686
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NCBI登录号
- NM_002486, NP_002477
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UniProt
- Q09161
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途径
- Ribonucleoprotein Complex Subunit Organization, Photoperiodism, Methionine Biosynthetic Process
抗原
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