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FMR1 抗体 (C-Term)

This anti-FMR1 antibody is a 兔 多克隆 antibody detecting FMR1 in WB. Suitable for 人, 小鼠, 大鼠, 犬, 兔, Cow 和 豚鼠.
产品编号 ABIN2778785
发货至: 中国

Quick Overview for FMR1 抗体 (C-Term) (ABIN2778785)

抗原

See all FMR1 抗体
FMR1 (Fragile X Mental Retardation 1 (FMR1))

适用

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人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠

宿主

  • 62
  • 19
  • 2

克隆类型

  • 55
  • 28
多克隆

标记

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This FMR1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    序列

    QIGASSRPPP NRTDKEKGYV TDDGQGMGRG SRPYRNRGHG RRGPGYTSES

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against Fmr1. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide corresponding to a region of Rat
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 593 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    FMR1 (Fragile X Mental Retardation 1 (FMR1))

    别名

    Fmr1

    背景

    Fmr1 is a translation repressor. Fmr1 is a component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates translation repression. RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs.Fmr1 is associated with polysomes. Fmr1 is involved in the transport of mRNA from the nucleus to the cytoplasm. Fmr1 binds strongly to poly(G), binds moderately to poly(U) but shows very little binding to poly(A) or poly(C).
    Alias Symbols: FMRP, Fmr1
    Protein Interaction Partner: Ubc,
    Protein Size: 593

    分子量

    67 kDa

    基因ID

    24948

    NCBI登录号

    NM_052804, NP_434691

    UniProt

    Q80WE1

    途径

    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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