EIF4E 抗体 (C-Term)
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Quick Overview for EIF4E 抗体 (C-Term) (ABIN2778784)
抗原
See all EIF4E 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- TECENREAVT HIGRVYKERL GLPPKIVIGY QSHADTATKS GSTTKNRFVV
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against EIF4E. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human EIF4E
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anti-Eukaryotic Translation Initiation Factor 4E (EIF4E) (AA 121-217) antibody
EIF4E 适用: 人, 大鼠 WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 4E (EIF4E) (AA 1-100) antibodyEIF4E 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 4E (EIF4E) antibodyEIF4E 适用: 人 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 5D11 unconjugated
anti-Eukaryotic Translation Initiation Factor 4E (EIF4E) (pSer209) antibodyEIF4E 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 4E (EIF4E) (C-Term) antibodyEIF4E 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 4E (EIF4E) antibodyEIF4E 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 4E (EIF4E) (pSer209) antibodyEIF4E 适用: 人, 大鼠, 小鼠, 斑马鱼 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 4E (EIF4E) (pSer209) antibodyKD Validated EIF4E 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB3235 unconjugated Recombinant Antibody
anti-Eukaryotic Translation Initiation Factor 4E (EIF4E) antibodyKD Validated EIF4E 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB3135 unconjugated Recombinant Antibody
anti-Eukaryotic Translation Initiation Factor 4E (EIF4E) (pSer209) antibodyEIF4E 适用: 人, 大鼠, 小鼠 WB, IHC (p), IF (cc) 宿主: 兔 Monoclonal 2B1 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 217 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))
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别名
- EIF4E
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背景
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All eukaryotic cellular mRNAs are blocked at their 5-prime ends with the 7-methylguanosine cap structure, m7GpppX (where X is any nucleotide). This structure is involved in several cellular processes including enhanced translational efficiency, splicing, mRNA stability, and RNA nuclear export. EIF4E is a eukaryotic translation initiation factor involved in directing ribosomes to the cap structure of mRNAs. It is a 24-kD polypeptide that exists as both a free form and as part of a multiprotein complex termed EIF4F. The EIF4E polypeptide is the rate-limiting component of the eukaryotic translation apparatus and is involved in the mRNA-ribosome binding step of eukaryotic protein synthesis. The other subunits of EIF4F are a 50-kD polypeptide, termed EIF4A (see MIM 601102), that possesses ATPase and RNA helicase activities, and a 220-kD polypeptide, EIF4G All eukaryotic cellular mRNAs are blocked at their 5-prime ends with the 7-methylguanosine cap structure, m7GpppX (where X is any nucleotide). This structure is involved in several cellular processes including enhanced translational efficiency, splicing, mRNA stability, and RNA nuclear export. EIF4E is a eukaryotic translation initiation factor involved in directing ribosomes to the cap structure of mRNAs. It is a 24-kD polypeptide that exists as both a free form and as part of a multiprotein complex termed EIF4F. The EIF4E polypeptide is the rate-limiting component of the eukaryotic translation apparatus and is involved in the mRNA-ribosome binding step of eukaryotic protein synthesis. The other subunits of EIF4F are a 50-kD polypeptide, termed EIF4A (see MIM 601102), that possesses ATPase and RNA helicase activities, and a 220-kD polypeptide, EIF4G (MIM 600495) (Rychlik et al., 1987 [PubMed 3469651]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CBP, EIF4E1, EIF4EL1, EIF4F, MGC111573
Protein Interaction Partner: EIF4EBP1, UBXN11, EIF4ENIF1, KANK2, TRIM22, EIF4EBP3, TDO2, TRIM27, EIF4G1, EIF4EBP2, EIF3B, RPS6KB1, MTOR, PML, NANS, PROSC, AHSA1, PEPD, EIF6, HSPD1, HSPA9, TYMP, CAPN1, ASS1, GEMIN5, PRDM4, CD83, UBC, ITGA4, APP, EIF4H, RPTOR, EIF4A1, RPS6KA5, HSPB2, E
Protein Size: 217 -
分子量
- 25 kDa
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基因ID
- 1977
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NCBI登录号
- NM_001968, NP_001959
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UniProt
- P06730
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途径
- BCR Signaling
抗原
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