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SNRNP70 抗体 (N-Term)

Cited in 2+ publications. This anti-SNRNP70 antibody is a 兔 多克隆 antibody detecting SNRNP70 in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, 犬, 斑马鱼, Cow, 豚鼠, 兔 和 马.
产品编号 ABIN2778715
发货至: 中国
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Quick Overview for SNRNP70 抗体 (N-Term) (ABIN2778715)

抗原

See all SNRNP70 抗体
SNRNP70 (Small Nuclear Ribonucleoprotein 70kDa (U1) (SNRNP70))

适用

  • 20
  • 9
  • 7
  • 5
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  • 4
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  • 2
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人, 小鼠, 大鼠, 犬, 斑马鱼, Cow, 豚鼠, 兔, 马

宿主

  • 20

克隆类型

  • 20
多克隆

标记

  • 15
  • 1
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This SNRNP70 antibody is un-conjugated

应用范围

  • 19
  • 10
  • 9
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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 7
    • 2
    • 1
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    • 1
    • 1
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    N-Term

    序列

    PHNDPNAQGD AFKTLFVARV NYDTTESKLR REFEVYGPIK RIHMVYSKRS

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against SNRP70. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human SNRP70
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 437 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Wang, Mueller, Hertel, Cambi: "G Run-mediated recognition of proteolipid protein and DM20 5' splice sites by U1 small nuclear RNA is regulated by context and proximity to the splice site." in: The Journal of biological chemistry, Vol. 286, Issue 6, pp. 4059-71, (2011) (PubMed).

    Wang, Cambi: "Heterogeneous nuclear ribonucleoproteins H and F regulate the proteolipid protein/DM20 ratio by recruiting U1 small nuclear ribonucleoprotein through a complex array of G runs." in: The Journal of biological chemistry, Vol. 284, Issue 17, pp. 11194-204, (2009) (PubMed).

  • 抗原

    SNRNP70 (Small Nuclear Ribonucleoprotein 70kDa (U1) (SNRNP70))

    别名

    SNRP70

    背景

    SNRP70 contains 1 RRM (RNA recognition motif) domain and mediates the splicing of pre-mRNA by binding to the loop I region of U1-snRNA. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.
    Alias Symbols: RPU1, Snp1, U1AP, U170K, U1RNP, RNPU1Z, SNRP70, U1-70K
    Protein Interaction Partner: IL32, UBC, NEDD8, LIN28A, EZH2, SUZ12, EED, RNF2, rev, WBP4, SRPK2, SRPK1, MYC, SRPK3, HDAC2, PAN2, SMURF2, PRPF40A, CDKL3, RNF11, PRKD2, SKIL, RELA, RASGRF1, SMAD9, SMAD5, SMAD4, SMAD3, SMAD2, CHERP, PRMT5, UBL4A, VCAM1, SMAD1, ITGA4, IL7R, IFIT3, IFIT1,
    Protein Size: 437

    分子量

    52 kDa

    基因ID

    6625

    NCBI登录号

    NM_003089, NP_003080

    UniProt

    P08621
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