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SF3B1 抗体 (Middle Region)

This anti-SF3B1 antibody is a 兔 多克隆 antibody detecting SF3B1 in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 山羊, 兔 和 斑马鱼.
产品编号 ABIN2778699
发货至: 中国

Quick Overview for SF3B1 抗体 (Middle Region) (ABIN2778699)

抗原

See all SF3B1 抗体
SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))

适用

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人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 山羊, 兔, 斑马鱼

宿主

  • 57
  • 4

克隆类型

  • 42
  • 19
多克隆

标记

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This SF3B1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 15
    • 6
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    Middle Region

    序列

    LLNDIPQSTE QYDPFAEHRP PKIADREDEY KKHRRTMIIS PERLDPFADG

    预测反应

    Cow: 100%, Dog: 100%, Goat: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

    产品特性

    This is a rabbit polyclonal antibody against SF3B1. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human SF3B1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 789 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))

    别名

    SF3B1

    背景

    SF3B1 is the subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome.
    Alias Symbols: MDS, PRP10, Hsh155, PRPF10, SAP155, SF3b155
    Protein Interaction Partner: SART3, SUMO2, SUMO3, MDM2, STAU1, UBC, LGR4, WWOX, RPA3, RPA2, RPA1, ERG, EED, RNF2, EZH2, SUZ12, APBB1, PRPF40A, WBP4, TCERG1, FBXO6, RBM17, SNIP1, SF3B6, WHSC1, RPS2, RPL23A, RPL18A, RPL10, RPL3, PLRG1, SMAD9, SMAD5, SMAD1, IL7R, FN1, ESR1, CSNK2A1, EIF
    Protein Size: 789

    分子量

    87 kDa

    基因ID

    23451

    NCBI登录号

    NM_001005526

    UniProt

    O75533

    途径

    Chromatin Binding
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