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AIF 抗体 (C-Term)

The 兔多克隆 anti-AIF antibody is suitable to detect AIF in samples from 人, 大鼠, 小鼠, Cow, 犬, Pig, 绵羊, 马, 兔, 斑马鱼和豚鼠. It has been validated for WB, IHC 和 IP.

Host: Rabbit Target Name: AIFM1 Sample Tissue: Mouse Liver Antibody Dilution: 1ug/ml (AIF 抗体 (C-Term))

Rabbit Anti-AIFM1 Antibody Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue Observed Staining: Cytoplasmic, nucleus Primary Antibody Concentration: 1:100 Other Working Concentrations: 1:600 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0. (AIF 抗体 (C-Term))

IHC

Rabbit Anti-AIFM1 Antibody Formalin Fixed Paraffin Embedded Tissue: Human Kidney Tissue Observed Staining: Cytoplasm Primary Antibody Concentration: 1:100 Other Working Concentrations: 1:600 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0. (AIF 抗体 (C-Term))

IHC

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产品编号 ABIN2778665

发货至: 中国

Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111

No. 88 KeChuang 6th Street

Beijing Economic Technological Development Area

Room 801-803

4A Biotech Co.,Ltd.

Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for AIF 抗体 (C-Term) (ABIN2778665)

抗原

See all AIF (AIFM1) 抗体

AIF (AIFM1) (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))

适用

人, 大鼠, 小鼠, Cow, 犬, Pig, 绵羊, 马, 兔, 斑马鱼, 豚鼠

宿主

兔

克隆类型

多克隆

标记

This AIF antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Discover our top product AIFM1 Primary Antibody

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C-Term

原理

PDCD8 Antibody - C-terminal region

序列

VDSSLPTVGV FAKATAQDNP KSATEQSGTG IRSESETESE ASEITIPPST

预测反应

Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%, Zebrafish: 79%

产品特性

This is a rabbit polyclonal antibody against PDCD8. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the C terminal region of human PDCD8
anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (AA 131-230) antibody
AIFM1 适用: 人 WB, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) antibody
AIFM1 适用: 人, 大鼠, 小鼠, 猴 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 4E7 unconjugated

anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (AA 103-322) antibody
AIFM1 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (C-Term) antibody
Verified AIFM1 适用: 人, 大鼠, 小鼠, Pig WB, IHC, ELISA, IF 宿主: 山羊 Polyclonal unconjugated

anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (AA 334-613) antibody
AIFM1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) antibody
KD Validated AIFM1 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 25GB2810 unconjugated Recombinant Antibody

anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (C-Term) antibody
AIFM1 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (AA 183-195) antibody
Verified AIFM1 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 山羊 Polyclonal unconjugated

anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (AA 70-98), (N-Term) antibody
AIFM1 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB22966 unconjugated

anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (C-Term) antibody
AIFM1 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ICC, FACS 宿主: 小鼠 Monoclonal 2I5 unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

说明

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP40199-100UG

限制

仅限研究用
状态

Liquid

浓度

0.5 mg/mL

缓冲液

Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

prevent freeze-thaw cycles

储存条件

4 °C,-20 °C

储存方法

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
抗原

AIF (AIFM1) (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))

别名

PDCD8

背景

Background Information: AIFM1 (PDCD8) is a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, AIFM1 induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9.This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Three alternative transcripts encoding different isoforms have been identified for this gene.
Gene Name: Apoptosis-inducing factor, mitochondrion-associated, 1
Alternative Symbols: AIF, AUNX1, CMT2D, CMTX4, COWCK, DFNX5, NADMR, NAMSD, PDCD8, COXPD6, SEMDHL
Protein Name: Apoptosis-inducing factor 1, mitochondrial

分子量

36kDa

基因ID

9131

NCBI登录号

NP_665812

UniProt

O95831

途径

Apoptosis, Positive Regulation of Endopeptidase Activity, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Warburg Effect