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GAPDH 抗体 (N-Term)

Cited in 2+ publications. This 兔 多克隆 anti-GAPDH antibody specifically detects GAPDH in WB 和 IHC. The antibody is reactive with 人, 小鼠, 大鼠, 兔, 犬, 绵羊, Cow, 马, 山羊 和 豚鼠 samples.
产品编号 ABIN2778645
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for GAPDH 抗体 (N-Term) (ABIN2778645)

抗原

See all GAPDH 抗体
GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH))

适用

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人, 小鼠, 大鼠, 兔, 犬, 绵羊, Cow, 马, 山羊, 豚鼠

宿主

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克隆类型

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多克隆

标记

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This GAPDH antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    N-Term

    序列

    IDLNYMVYMF QYDSTHGKFH GTVKAENGKL VINGNPITIF QERDPSKIKW

    预测反应

    Cow: 93%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Sheep: 100%

    产品特性

    This is a rabbit polyclonal antibody against GAPDH. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human GAPDH
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 335 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Kalinec, Thein, Parsa, Yorgason, Luxford, Urrutia, Kalinec: "Acetaminophen and NAPQI are toxic to auditory cells via oxidative and endoplasmic reticulum stress-dependent pathways." in: Hearing research, Vol. 313, pp. 26-37, (2014) (PubMed).

    Fu, Mukhamedova, Ip, DSouza, Henley, DiTommaso, Kesani, Ditiatkovski, Jones, Lane, Jennings, Smyth, Kile, Sviridov: "ABCA12 regulates ABCA1-dependent cholesterol efflux from macrophages and the development of atherosclerosis." in: Cell metabolism, Vol. 18, Issue 2, pp. 225-38, (2013) (PubMed).

  • 抗原

    GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH))

    别名

    GAPDH

    背景

    GAPDH catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The enzyme exists as a tetramer of identical chains. Many pseudogenes similar to this locus are present in the human genome.Glyceraldehyde-3-phosphate dehydrogenase catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The enzyme exists as a tetramer of identical chains. A GAPD pseudogene has been mapped to Xp21-p11 and 15 GAPD-like loci have been identified. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: G3PD, GAPD, MGC88685
    Protein Interaction Partner: FUS, HUWE1, UBC, SUMO2, SUMO3, STAU1, MDM2, GAPDH, ASB15, ASB16, RPA3, RPA2, RPA1, EED, SNCA, rev, HSPA9, HSPA1L, GAS7, TUBA1A, TUFM, RAP1GDS1, PPP5C, PPIB, YWHAG, TUBB, TUBA1C, PRPF40A, UBQLN1, DCPS, MAT2B, ACOT7, METAP2, FERMT2, GBP1, EEF1A1, TYMP, DFFA
    Protein Size: 335

    分子量

    36 kDa

    基因ID

    2597

    NCBI登录号

    NM_002046, NP_002037

    UniProt

    Q2TSD0
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