RNF34 抗体 (Middle Region)
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北京 101111
Quick Overview for RNF34 抗体 (Middle Region) (ABIN2778633)
抗原
See all RNF34 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- LVDLVLCHHG LGSEDDMDTS SLNSSRSQTS SFFTRSFFSN YTAPSATMSS
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预测反应
- Cow: 87%, Dog: 93%, Guinea Pig: 80%, Horse: 93%, Human: 100%, Rabbit: 80%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against RNF34. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human RNF34
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anti-Ring Finger Protein 34 (RNF34) (AA 1-220) antibody
RNF34 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 34 (RNF34) (AA 1-373) antibodyRNF34 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Ring Finger Protein 34 (RNF34) (AA 143-192) antibodyRNF34 适用: 人, Cow, 兔, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 34 (RNF34) (Middle Region) antibodyRNF34 适用: 人, Cow, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 372 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- RNF34 (Ring Finger Protein 34 (RNF34))
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别名
- RNF34
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背景
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RNF34 contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis.The protein encoded by this gene contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Alias Symbols: FLJ21786, RFI, RIF, RIFF, hRFI, CARP1, CARP-1
Protein Interaction Partner: APPBP2, NOD1, APP, PRKACB, PHF7, TRIM23, UBE2D2, CASP10, CASP8, FZR1, ANAPC2, CDC20, SH3KBP1, PPARGC1A, TP53, UBE2F, UBE2H, DNAJA3,
Protein Size: 372 -
分子量
- 42 kDa
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基因ID
- 80196
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NCBI登录号
- NM_025126, NP_079402
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UniProt
- Q969K3
抗原
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