Kdm6b 抗体 (Middle Region)
Quick Overview for Kdm6b 抗体 (Middle Region) (ABIN2778611)
抗原
See all Kdm6b 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- AGLQGVVVLE QYRTEELAQA YDAFTLVRAR RARGQRRRAL GQAAGTGFGS
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预测反应
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against JMJD3. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human JMJD3
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 644 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Kdm6b (Lysine (K)-Specific Demethylase 6B (Kdm6b))
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别名
- JMJD3
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背景
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JMJD3 is a histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. It plays a central role in regulation of posterior development, by regulating HOX gene expression. It is involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation.
Alias Symbols: KIAA0346, JMJD3
Protein Interaction Partner: WDR5, ASH2L, RBBP5, UBC, TK1, CSNK2B, HIST1H3A, WAS, SMAD3, SMAD2, SMAD4, SMAD1,
Protein Size: 1643 -
分子量
- 177 kDa
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基因ID
- 23135
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NCBI登录号
- NM_001080424
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UniProt
- O15054
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途径
- Warburg Effect
抗原
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