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Kdm6b 抗体 (Middle Region)

This anti-Kdm6b antibody (ABIN2778611) is a Rabbit Polyclonal antibody detecting Kdm6b in WB. Suitable for Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Pig.
产品编号 ABIN2778611
发货至: 中国

Quick Overview for Kdm6b 抗体 (Middle Region) (ABIN2778611)

抗原

See all Kdm6b 抗体
Kdm6b (Lysine (K)-Specific Demethylase 6B (Kdm6b))

适用

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人, 小鼠, 大鼠, 犬, Cow, 马, 兔, Pig

宿主

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克隆类型

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多克隆

标记

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This Kdm6b antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Middle Region

    序列

    AGLQGVVVLE QYRTEELAQA YDAFTLVRAR RARGQRRRAL GQAAGTGFGS

    预测反应

    Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against JMJD3. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human JMJD3
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 644 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    Kdm6b (Lysine (K)-Specific Demethylase 6B (Kdm6b))

    别名

    JMJD3

    背景

    JMJD3 is a histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. It plays a central role in regulation of posterior development, by regulating HOX gene expression. It is involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation.
    Alias Symbols: KIAA0346, JMJD3
    Protein Interaction Partner: WDR5, ASH2L, RBBP5, UBC, TK1, CSNK2B, HIST1H3A, WAS, SMAD3, SMAD2, SMAD4, SMAD1,
    Protein Size: 1643

    分子量

    177 kDa

    基因ID

    23135

    NCBI登录号

    NM_001080424

    UniProt

    O15054

    途径

    Warburg Effect
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