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Aprataxin 抗体 (C-Term)

Name: Aprataxin 抗体 (C-Term)
SKU: ABIN2778569
Availability: OutOfStock

This anti-Aprataxin antibody is a 兔多克隆 antibody detecting Aprataxin in IHC 和 WB. Suitable for 人, 小鼠, 大鼠, 豚鼠, 犬, 马, 兔和 Cow. This Primary Antibody has been cited in 1 publication.

WB Suggested Anti-APTX Antibody Titration: 2. (Aprataxin 抗体 (C-Term))

IHC

2 images

(1 reference)

产品编号 ABIN2778569

发货至: 中国

Quick Overview for Aprataxin 抗体 (C-Term) (ABIN2778569)

抗原

See all Aprataxin (APTX) 抗体

Aprataxin (APTX)

适用

人, 小鼠, 大鼠, 豚鼠, 犬, 马, 兔, Cow

宿主

兔

克隆类型

多克隆

标记

This Aprataxin antibody is un-conjugated

应用范围

Immunohistochemistry (IHC), Western Blotting (WB)

Discover our top product APTX Primary Antibody

抗原表位
6

2

2

1

1

1

1

1

1

1

1
C-Term

序列

VIEMVQEAGR VTVRDGMPEL LKLPLRCHEC QQLLPSIPQL KEHLRKHWTQ

预测反应

Cow: 100%, Dog: 92%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

产品特性

This is a rabbit polyclonal antibody against APTX. It was validated on Western Blot and immunohistochemistry.

纯化方法

Protein A purified

免疫原

The immunogen is a synthetic peptide directed towards the C terminal region of human APTX
anti-Aprataxin (APTX) (AA 69-166) antibody
APTX 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 2H6 unconjugated

anti-Aprataxin (APTX) (AA 93-342) antibody
APTX 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Aprataxin (APTX) antibody
APTX 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Aprataxin (APTX) (AA 1-254) antibody
APTX 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

anti-Aprataxin (APTX) (C-Term) antibody
APTX 适用: 人, 小鼠, 大鼠, 豚鼠, Cow, 猴, Pig, Bat, Hamster IHC, WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Aprataxin (APTX) antibody
APTX 适用: 人, 小鼠, 大鼠 IHC, WB, IF, IC 宿主: 兔 Polyclonal unconjugated

anti-Aprataxin (APTX) (AA 92-161) antibody
APTX 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Aprataxin (APTX) (N-Term) antibody
APTX 适用: 人, 豚鼠, 犬, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated

anti-Aprataxin (APTX) (AA 108-157) antibody
APTX 适用: 人, 豚鼠, 犬, Cow, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated

anti-Aprataxin (APTX) (N-Term) antibody
APTX 适用: 人, 小鼠, 大鼠, 豚鼠, 犬, 马, 兔 IHC, WB 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 342 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Dopeso, Mateo-Lozano, Elez, Landolfi, Ramos Pascual, Hernández-Losa, Mazzolini, Rodrigues, Bazzocco, Carreras, Espín, Armengol, Wilson, Mariadason, Ramon Y Cajal, Tabernero, Schwartz, Arango: "Aprataxin tumor levels predict response of colorectal cancer patients to irinotecan-based treatment." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 16, Issue 8, pp. 2375-82, (2010) (PubMed).
抗原

Aprataxin (APTX)

别名

APTX

背景

APTX is a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. APTX may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia.This gene encodes a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. The encoded protein may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia. Multiple transcript variants encoding distinct isoforms have been identified for this gene, however, the full length nature of some variants has not been determined.This gene encodes a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. The encoded protein may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia. Multiple transcript variants encoding distinct isoforms have been identified for this gene, however, the full length nature of some variants has not been determined.
Alias Symbols: AOA, AOA1, AXA1, EAOH, EOAHA, FHA-HIT
Protein Interaction Partner: PNMA1, UBC, SUMO1, NEDD8, LIG3, HSPA4, XRCC1, DDX21, CNTROB, TSPYL2, CALCOCO1, SYT17, ZNF639, MAPKBP1, CEP350, PICK1, XRCC4, TRIM37, MBP, HIVEP1, BANF1, PARP1, TP53,
Protein Size: 342

分子量

38 kDa

基因ID

54840

NCBI登录号

NM_175073, NP_778243

UniProt

Q6JV85

途径

DNA Damage Repair, Chromatin Binding