GLIS3 抗体 (N-Term)
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北京 101111
Quick Overview for GLIS3 抗体 (N-Term) (ABIN183860)
抗原
See all GLIS3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- GLIS3 Antibody - N-terminal region
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序列
- PPASQVSTAC NQISPSLQRA MNAANLNIPP SDTRSLISRE SLASTTLSLT
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预测反应
- Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against GLIS3. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human GLIS3
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP39924-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- GLIS3 (GLIS Family Zinc Finger 3 (GLIS3))
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别名
- GLIS3
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背景
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Background Information: GLIS3 is a member of the GLI-similar zinc finger protein family and has five C2H2-type zinc finger domains. GLIS3 functions as both a repressor and activator of transcription and is specifically involved in the development of pancreatic beta cells, the thyroid, eye, liver and kidney. Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH).
Gene Name: GLIS family zinc finger 3
Alternative Symbols: NDH, ZNF515
Protein Name: Zinc finger protein GLIS3
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分子量
- 84kDa
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基因ID
- 169792
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NCBI登录号
- NP_689842
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UniProt
- Q8NEA6
抗原
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