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SIAH1 抗体 (N-Term)

This anti-SIAH1 antibody is a 兔 多克隆 antibody detecting SIAH1 in WB 和 IHC. Suitable for 人, 大鼠, 小鼠, 犬, 斑马鱼, Cow, 豚鼠, 马 和 兔.
产品编号 ABIN2778297
发货至: 中国

Quick Overview for SIAH1 抗体 (N-Term) (ABIN2778297)

抗原

See all SIAH1 抗体
SIAH1 (E3 Ubiquitin-Protein Ligase SIAH1 (SIAH1))

适用

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人, 大鼠, 小鼠, 犬, 斑马鱼, Cow, 豚鼠, 马, 兔

宿主

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  • 2
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克隆类型

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多克隆

标记

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This SIAH1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    N-Term

    序列

    FTCLPAARTR KRKEMSRQTA TALPTGTSKC PPSQRVPALT GTTASNNDLA

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

    产品特性

    This is a rabbit polyclonal antibody against SIAH1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human SIAH1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 313 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    SIAH1 (E3 Ubiquitin-Protein Ligase SIAH1 (SIAH1))

    别名

    SIAH1

    背景

    SIAH1 is a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.
    Alias Symbols: SIAH1A
    Protein Interaction Partner: MX1, MAB21L1, KIFC3, KCNJ10, INHA, UBE2K, FLI1, EEF1D, PHC2, PHC1, CDC34, CAPG, BCL6, TRIM23, AQP1, PFKM, ZCCHC13, MTIF3, UPP2, MOB3C, SPATA4, PRR20A, HIST4H4, EXOC3-AS1, PTPMT1, RPS19BP1, SPATC1L, KATNAL1, TRIM7, GDPD5, ZBP1, KIAA1683, ARMC9, KIAA0319L,
    Protein Size: 313

    分子量

    35 kDa

    基因ID

    6477

    NCBI登录号

    NM_001006610, NP_001006611
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