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PPARA 抗体 (Middle Region)

This anti-PPARA antibody is a 兔 多克隆 antibody detecting PPARA in WB. Suitable for 人, 小鼠, 大鼠, 犬, 马, Pig, 山羊, 豚鼠, 兔 和 绵羊.
产品编号 ABIN2778267
发货至: 中国

Quick Overview for PPARA 抗体 (Middle Region) (ABIN2778267)

抗原

See all PPARA 抗体
PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))

适用

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人, 小鼠, 大鼠, 犬, 马, Pig, 山羊, 豚鼠, 兔, 绵羊

宿主

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克隆类型

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多克隆

标记

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This PPARA antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Middle Region

    序列

    IYEAYLKNFN MNKVKARVIL SGKASNNPPF VIHDMETLCM AEKTLVAKLV

    预测反应

    Dog: 92%, Goat: 91%, Guinea Pig: 77%, Horse: 92%, Human: 100%, Mouse: 85%, Pig: 92%, Rabbit: 85%, Rat: 85%, Sheep: 91%

    产品特性

    This is a rabbit polyclonal antibody against PPARA. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human PPARA
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 468 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))

    别名

    PPARA

    背景

    Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers, this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals which contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor.
    Alias Symbols: PPAR, NR1C1, hPPAR, PPARalpha
    Protein Interaction Partner: SIRT1, PRMT1, PRMT8, RXRA, CHD9, NCOA1, FOXA3, CDK3, TNP1, HSP90AA1, NCOR2, NCOR1, SUMO1, UBE2I, LPIN1, SRC, TRA, MECR, STAC3, HELZ2, NRBF2, AIP, NR1H3, MED24, GADD45G, GADD45B, AKAP13, PPARGC1A, MED1, EP300, NRIP1, DAP3, MAPK3, DUT, RXRG, PRKCD, PRKCA, M
    Protein Size: 468

    分子量

    51 kDa

    基因ID

    5465

    NCBI登录号

    NM_005036, NP_005027

    UniProt

    Q07869

    途径

    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Hepatitis C
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