RGS17 抗体 (C-Term)
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Quick Overview for RGS17 抗体 (C-Term) (ABIN2778238)
抗原
See all RGS17 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- NRNLLDPNPH MYEDAQLQIY TLMHRDSFPR FLNSQIYKSF VESTAGSSSE
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against RGS17. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human RGS17
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- RGS17 (Regulator of G-Protein Signaling 17 (RGS17))
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别名
- RGS17
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背景
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This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.
Alias Symbols: RGS-17, RGSZ2, hRGS17
Protein Interaction Partner: LCE3C, LCE2A, LCE4A, TBC1D16, DHX37, NUFIP2, PTGER3, OTX1, RPL10A, SMCP, HOXA1, GNAI3, GNAI1, AQP1, ADRB2, RABEP1, RBBP8, UBC, OSTM1,
Protein Size: 210 -
分子量
- 23 kDa
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基因ID
- 26575
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NCBI登录号
- NM_012419, NP_036551
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UniProt
- Q9UGC6
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途径
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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