RGS17 抗体 (AA 70-150)
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Quick Overview for RGS17 抗体 (AA 70-150) (ABIN7231022)
抗原
See all RGS17 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 70-150
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原理
- Rabbit Anti-RGS17 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of RGS17 protein
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human RGS17 protein at AA range: 70-150
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- RGS17 (Regulator of G-Protein Signaling 17 (RGS17))
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别名
- RGS17
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背景
- Regulator of G-protein signaling 17, RGS17RGS17 (Regulator Of G Protein Signaling 17) encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.
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分子量
- 23kD
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基因ID
- 26575
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UniProt
- Q9UGC6
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途径
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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