TUB 抗体 (N-Term)
Quick Overview for TUB 抗体 (N-Term) (ABIN2777955)
抗原
See all TUB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- DSLASVQLGA TRPTAPASAK RTKAAATAGG QGGAARKEKK GKHKGTSGPA
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预测反应
- Dog: 92%, Guinea Pig: 85%, Horse: 85%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 92%
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产品特性
- This is a rabbit polyclonal antibody against TUB. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human TUB
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 561 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- TUB (Tubby Homolog (TUB))
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别名
- TUB
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背景
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TUB functions in signal transduction from heterotrimeric G protein-coupled receptors. It could be involved in the hypothalamic regulation of body weight. This gene encodes a member of the Tubby family of bipartite transcription factors. The encoded protein may play a role in obesity and sensorineural degradation. The crystal structure has been determined for a similar protein in mouse, and it functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis. Two transcript variants encoding distinct isoforms have been identified for this gene.
Alias Symbols: rd5
Protein Interaction Partner: UBC, SUV420H2, GNAQ, SRC, ABL1, PLCG1, PIK3R1, LCK, JAK2, IRS1, GRB2,
Protein Size: 561 -
分子量
- 62 kDa
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基因ID
- 7275
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NCBI登录号
- NM_003320, NP_003311
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UniProt
- P50607
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途径
- RTK signaling, Sensory Perception of Sound
抗原
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