BAF53A 抗体 (N-Term)
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北京 101111
Quick Overview for BAF53A 抗体 (N-Term) (ABIN2777881)
抗原
See all BAF53A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- ACTL6A Antibody - N-terminal region
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序列
- VDFPTAIGMV VERDDGSTLM EIDGDKGKQG GPTYYIDTNA LRVPRENMEA
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against ACTL6A. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ACTL6A
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP33350-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- BAF53A (Actin-Like 6A (BAF53A))
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别名
- ACTL6A
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背景
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Background Information: This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila, the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described.
Gene Name: Actin-like 6A
Alternative Symbols: Arp4, ACTL6, BAF53A, INO80K, ARPN-BETA
Protein Name: Actin-like protein 6A
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分子量
- 47kDa
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基因ID
- 86
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NCBI登录号
- NP_004292
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UniProt
- O96019
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途径
- Chromatin Binding, Photoperiodism
抗原
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