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BAF53A 抗体 (N-Term)

This anti-BAF53A antibody is a 兔 多克隆 antibody detecting BAF53A in WB. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 马, 兔 和 豚鼠.
产品编号 ABIN2777881
发货至: 中国

Quick Overview for BAF53A 抗体 (N-Term) (ABIN2777881)

抗原

See all BAF53A 抗体
BAF53A (Actin-Like 6A (BAF53A))

适用

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人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠

宿主

  • 74
  • 5

克隆类型

  • 63
  • 16
多克隆

标记

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This BAF53A antibody is un-conjugated

应用范围

  • 62
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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    VDFPTAIGMV VERDDGSTLM EIDGDKGKQG GPTYYIDTNA LRVPRENMEA

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against ACTL6A. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human ACTL6A
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 429 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    BAF53A (Actin-Like 6A (BAF53A))

    别名

    ACTL6A

    背景

    This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila, the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described.
    Alias Symbols: ACTL6, BAF53A, MGC5382, Arp4, INO80K, ARPN-BETA
    Protein Interaction Partner: UBC, BMI1, HECW2, FBXO6, HDAC2, CBX5, UCHL5, ARID1B, RUVBL1, TRRAP, ARID1A, SMARCE1, SMARCC2, SMARCC1, SMARCA4, SMARCA2, UBD, GRB2, INO80E, CAND1, CUL3, CDK9, CDK2, H2AFZ, TP53, UL27, SMARCD1, HDGF, SOX2, SMARCAD1, KAT5, PBRM1, Bcl7b, INO80C, ACTR8, INO80
    Protein Size: 429

    分子量

    47 kDa

    基因ID

    86

    NCBI登录号

    NM_004301, NP_004292

    UniProt

    O96019

    途径

    Chromatin Binding, Photoperiodism
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