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Sp3 抗体 (Middle Region)

This anti-Sp3 antibody is a 兔 多克隆 antibody detecting Sp3 in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, 豚鼠, 马, 兔, Cow 和 犬.
产品编号 ABIN2777872
发货至: 中国

Quick Overview for Sp3 抗体 (Middle Region) (ABIN2777872)

抗原

See all Sp3 抗体
Sp3 (Sp3 Transcription Factor (Sp3))

适用

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  • 1
人, 小鼠, 大鼠, 豚鼠, 马, 兔, Cow, 犬

宿主

  • 38
  • 4

克隆类型

  • 38
  • 4
多克隆

标记

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  • 3
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  • 1
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This Sp3 antibody is un-conjugated

应用范围

  • 36
  • 20
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  • 7
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  • 3
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  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    • 7
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    Middle Region

    序列

    TAGINADGHL INTGQAMDSS DNSERTGERV SPDINETNTD TDLFVPTSSS

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against SP3. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human SP3
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 781 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    Sp3 (Sp3 Transcription Factor (Sp3))

    别名

    SP3

    背景

    SP3 is a transcriptional factor that can act as an activator or repressor, probably in a isoform-specific manner. SP3 binds to GT and GC boxes promoters elements.This gene belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. This protein contains a zinc finger DNA-binding domain and several transactivation domains, and has been reported to function as a bifunctional transcription factor that either stimulates or represses the transcription of numerous genes. Transcript variants encoding different isoforms have been described for this gene, and one has been reported to initiate translation from a non-AUG (AUA) start codon. Additional isoforms, resulting from the use of alternate downstream translation initiation sites, have also been noted.
    Alias Symbols: DKFZp686O1631, SPR-2, SPR2
    Protein Interaction Partner: SP1, SUMO1, PPP2R4, PPP1CC, GCH1, HLTF, TFAP4, YY1, SUMO2, UBC, RELA, MECP2, HDAC2, HDAC1, ZBTB7B, EP300, CRX, TP53, NKX3-1, CREBBP, CEBPB, ESR1, DNMT1, SFPQ, PIAS1, GRIN1, GABPA, ZBTB7A, UBE2I, STK19, RBBP4, E2F1, RB1, SP4, TNFSF10, SENP1,
    Protein Size: 781

    分子量

    82 kDa

    基因ID

    6670

    NCBI登录号

    NM_003111, NP_003102

    UniProt

    Q02447
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