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SOX10 抗体 (Middle Region)

Cited in 1 publication. This anti-SOX10 antibody is a 兔 多克隆 antibody detecting SOX10 in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠 和 马.
产品编号 ABIN2777864
发货至: 中国
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Quick Overview for SOX10 抗体 (Middle Region) (ABIN2777864)

抗原

See all SOX10 抗体
SOX10 (SRY (Sex Determining Region Y)-Box 10 (SOX10))

适用

人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 马

宿主

  • 102
  • 50
  • 2

克隆类型

  • 97
  • 57
多克隆

标记

  • 62
  • 14
  • 7
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SOX10 antibody is un-conjugated

应用范围

  • 116
  • 62
  • 48
  • 41
  • 40
  • 22
  • 16
  • 15
  • 15
  • 13
  • 12
  • 11
  • 4
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 56
    • 16
    • 8
    • 8
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    序列

    PGGEAEQGGT AAIQAHYKSA HLDHRHPGEG SPMSDGNPEH PSGQSHGPPT

    预测反应

    Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 86%

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human SOX10
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 466 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Wilson, Olm-Shipman, Acevedo, Palaniyandi, Hall, Kosa, Stumpff, Smith, Pitstick, Liao, Bjork, Czirok, Saadi: "SPECC1L deficiency results in increased adherens junction stability and reduced cranial neural crest cell delamination." in: Scientific reports, Vol. 6, pp. 17735, (2016) (PubMed).

  • 抗原

    SOX10 (SRY (Sex Determining Region Y)-Box 10 (SOX10))

    别名

    SOX10

    背景

    SOX10 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. This protein may act as a transcriptional activator after forming a protein complex with other proteins. It acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease.
    Alias Symbols: DOM, MGC15649, WS2E, WS4, PCWH, WS4C
    Protein Interaction Partner: UBC, CDK6, EXOC5, NMI, EPAS1, POU3F2, UTF1, PAX3, UBE2I, OLIG2, HHEX, PAX6, ALX4, PRRX2, SUMO2, POU3F3, SUMO3, SOX10, SUMO1, TCF12, MEOX1, DLX5, HIVEP1, SP1, PRRX1, JUN, POU5F1, HOXC4, HOXA3, EGR2, CEBPA,
    Protein Size: 466

    分子量

    50 kDa

    基因ID

    6663

    NCBI登录号

    NM_006941, NP_008872

    UniProt

    P56693

    途径

    Chromatin Binding
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