SOX5 抗体 (C-Term)
(12 references)Our Local Distributor
北京 101111
Quick Overview for SOX5 抗体 (C-Term) (ABIN2777862)
抗原
See all SOX5 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
序列
- PEPGMPVIQS TYGVKGEEPH IKEEIQAEDI NGEIYDEYDE EEDDPDVDYG
-
特异性
- Designed to recognize all five isoforms of human SOX5 (84, 82, 42, 71 and 83 kDa)
-
预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 100%
-
产品特性
- This is a rabbit polyclonal antibody against SOX5. It was validated on Western Blot.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human SOX5
-
-
anti-SRY (Sex Determining Region Y)-Box 5 (SOX5) (AA 1-120) antibody
SOX5 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 5 (SOX5) antibodySOX5 适用: 人, 大鼠, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 5 (SOX5) (AA 1-120) antibodySOX5 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 5 (SOX5) (AA 181-230) antibodySOX5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4H8 unconjugated
anti-SRY (Sex Determining Region Y)-Box 5 (SOX5) antibodySOX5 适用: 人, 大鼠, 小鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 5 (SOX5) (C-Term) antibodySOX5 适用: 人, 大鼠, 小鼠, Cow, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 5 (SOX5) (C-Term) antibodySOX5 适用: 人, 大鼠, 豚鼠, 马, 兔, Cow, 犬, Pig, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 5 (SOX5) (AA 56-105) antibodySOX5 适用: 人, 小鼠, 豚鼠, 马, 兔, Pig, 猴, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 5 (SOX5) antibodySOX5 适用: 人 WB 宿主: 小鼠 Monoclonal 2A8 unconjugated
anti-SRY (Sex Determining Region Y)-Box 5 (SOX5) antibodySOX5 适用: 人 DB, ICC 宿主: 小鼠 Monoclonal 7031C6a unconjugated
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 377 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
-
: "Transcriptional regulation of human sperm-associated antigen 16 gene by S-SOX5." in: BMC molecular biology, Vol. 18, Issue 1, pp. 2, (2017) (PubMed).
: "Alteration of rat fetal cerebral cortex development after prenatal exposure to polychlorinated biphenyls." in: PLoS ONE, Vol. 9, Issue 3, pp. e91903, (2014) (PubMed).
: "Similar properties of chondrocytes from osteoarthritis joints and mesenchymal stem cells from healthy donors for tissue engineering of articular cartilage." in: PLoS ONE, Vol. 8, Issue 5, pp. e62994, (2013) (PubMed).
: "Sonic Hedgehog-signalling patterns the developing chicken comb as revealed by exploration of the pea-comb mutation." in: PLoS ONE, Vol. 7, Issue 12, pp. e50890, (2012) (PubMed).
: "Array-based comparative genomic hybridization identifies CDK4 and FOXM1 alterations as independent predictors of survival in malignant peripheral nerve sheath tumor." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 7, pp. 1924-34, (2011) (PubMed).
: "SHOX interacts with the chondrogenic transcription factors SOX5 and SOX6 to activate the aggrecan enhancer." in: Human molecular genetics, Vol. 20, Issue 8, pp. 1547-59, (2011) (PubMed).
: "Transcriptional regulation of an axonemal central apparatus gene, sperm-associated antigen 6, by a SRY-related high mobility group transcription factor, S-SOX5." in: The Journal of biological chemistry, Vol. 285, Issue 40, pp. 30496-505, (2010) (PubMed).
: "Neoplasms with schwannian differentiation express transcription factors known to regulate normal schwann cell development." in: International journal of surgical pathology, Vol. 18, Issue 6, pp. 449-57, (2010) (PubMed).
: "Integration of neuronal clones in the radial cortical columns by EphA and ephrin-A signalling." in: Nature, Vol. 461, Issue 7263, pp. 524-8, (2009) (PubMed).
: "Copy number variation in intron 1 of SOX5 causes the Pea-comb phenotype in chickens." in: PLoS genetics, Vol. 5, Issue 6, pp. e1000512, (2009) (PubMed).
: "Sox5 can suppress platelet-derived growth factor B-induced glioma development in Ink4a-deficient mice through induction of acute cellular senescence." in: Oncogene, Vol. 28, Issue 12, pp. 1537-48, (2009) (PubMed).
: "Exploiting orthologue diversity for systematic detection of gain-of-function phenotypes." in: BMC genomics, Vol. 9, pp. 254, (2008) (PubMed).
-
: "Transcriptional regulation of human sperm-associated antigen 16 gene by S-SOX5." in: BMC molecular biology, Vol. 18, Issue 1, pp. 2, (2017) (PubMed).
-
- SOX5 (SRY (Sex Determining Region Y)-Box 5 (SOX5))
-
别名
- SOX5
-
背景
-
SOX5 encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The encoded protein may play a role in chondrogenesis. A pseudogene of this gene is located on chromosome 8.
Alias Symbols: L-SOX5, MGC35153
Protein Interaction Partner: SUMO1P1, MORN3, PRR20A, FAM46B, CBX8, ZNF581, ARID5A, KAT5, CDC23, TAF6, SOX5, LMO2, LMO1, KIFC3, CRX, AES, MED27, UQCRFS1, TTC1, RPS2, SMAD7, SMAD5, SMAD1, FTH1, CDK6, CDC25A, APP, SOX2, SOX6,
Protein Size: 377 -
分子量
- 42 kDa
-
基因ID
- 6660
-
NCBI登录号
- NM_178010, NP_821078
-
UniProt
- P35711
抗原
-
