PRDM16 抗体 (Middle Region)
Quick Overview for PRDM16 抗体 (Middle Region) (ABIN2777828)
抗原
See all PRDM16 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- LNHTQDAKLP SPLGNPALPL VSAVSNSSQG TTAAAGPEEK FESRLEDSCV
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预测反应
- Cow: 92%, Dog: 77%, Guinea Pig: 86%, Horse: 85%, Human: 100%, Mouse: 79%, Pig: 92%, Rat: 86%
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产品特性
- This is a rabbit polyclonal antibody against PRDM16. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human PRDM16
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anti-PR Domain Containing 16 (PRDM16) (AA 771-804) antibody
PRDM16 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB49517 unconjugated
anti-PR Domain Containing 16 (PRDM16) (AA 448-683) antibodyPRDM16 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-PR Domain Containing 16 (PRDM16) (C-Term) antibodyVerified PRDM16 适用: 人, 小鼠 ELISA, ChIP, FACS 宿主: 山羊 Polyclonal unconjugated
anti-PR Domain Containing 16 (PRDM16) (AA 779-996) antibodyPRDM16 适用: 人 WB 宿主: 小鼠 Monoclonal 1740CT793-52-44 unconjugated
anti-PR Domain Containing 16 (PRDM16) (AA 539-588) antibodyPRDM16 适用: 人, 小鼠, 犬, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-PR Domain Containing 16 (PRDM16) antibodyPRDM16 适用: 人, 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-PR Domain Containing 16 (PRDM16) (C-Term) antibodyPRDM16 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-PR Domain Containing 16 (PRDM16) (C-Term) antibodyPRDM16 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 1275 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PRDM16 (PR Domain Containing 16 (PRDM16))
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别名
- PRDM16
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背景
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The reciprocal translocation t(1,3)(p36,q21) occurs in a subset of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). This gene is located near the 1p36.3 breakpoint and has been shown to be specifically expressed in the t(1:3)(p36,q21)-positive MDS/AML. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal PR domain. The translocation results in the overexpression of a truncated version of this protein that lacks the PR domain, which may play an important role in the pathogenesis of MDS and AML. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Alias Symbols: KIAA1675, MEL1, PFM13
Protein Interaction Partner: TFAP4, UBC, HDAC2, Ctbp2, SUMO1, SKI, SMAD3, SMAD2, INADL,
Protein Size: 1275 -
分子量
- 140 kDa
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基因ID
- 63976
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NCBI登录号
- NM_022114, NP_071397
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UniProt
- Q9HAZ2
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途径
- Stem Cell Maintenance, Brown Fat Cell Differentiation
抗原
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