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Diazepam Binding Inhibitor 抗体 (N-Term)

This anti-Diazepam Binding Inhibitor antibody is a 兔 多克隆 antibody detecting Diazepam Binding Inhibitor in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 豚鼠 和 兔.
产品编号 ABIN2777771
发货至: 中国

Quick Overview for Diazepam Binding Inhibitor 抗体 (N-Term) (ABIN2777771)

抗原

See all Diazepam Binding Inhibitor (DBI) 抗体
Diazepam Binding Inhibitor (DBI)

适用

人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔

宿主

  • 45
  • 4

克隆类型

  • 46
  • 3
多克隆

标记

  • 27
  • 9
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Diazepam Binding Inhibitor antibody is un-conjugated

应用范围

  • 37
  • 28
  • 15
  • 14
  • 8
  • 6
  • 3
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 6
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    序列

    MSQAEFEKAA EEVRHLKTKP SDEEMLFIYG HYKQATVGDI NTERPGMLDF

    预测反应

    Cow: 86%, Dog: 79%, Guinea Pig: 92%, Human: 100%, Mouse: 85%, Rabbit: 86%, Rat: 92%

    产品特性

    This is a rabbit polyclonal antibody against DBI. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human DBI
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 87 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    Diazepam Binding Inhibitor (DBI)

    别名

    DBI

    背景

    DBI is diazepam binding inhibitor. The protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. DBI is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene. This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene.
    Alias Symbols: ACBD1, ACBP, CCK-RP, EP, MGC70414
    Protein Interaction Partner: UBC, MAP1LC3B, NSFL1C, DUSP23, NIPSNAP1, RAD23B, RAD23A, GSK3B, UBXN2A, TSPO, PPCDC,
    Protein Size: 87

    分子量

    10 kDa

    基因ID

    1622

    NCBI登录号

    NM_001079862, NP_001073331

    UniProt

    P07108
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