SUFUH 抗体 (N-Term)
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北京 101111
Quick Overview for SUFUH 抗体 (N-Term) (ABIN2777711)
抗原
See all SUFUH 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- SUFU Antibody - N-terminal region
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序列
- HAIYGECRRL YPDQPNPLQV TAIVKYWLGG PDPLDYVSMY RNVGSPSANI
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against SUFU. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human SUFU
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP33019-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- SUFUH (Suppressor of Fused Homolog (SUFUH))
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别名
- SUFU
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背景
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Background Information: SUFU is a component of the Sonic hedgehog (SHH, MIM 600725)/Patched (PTCH, MIM 601309) signaling pathway. Mutations in genes encoding components of this pathway are deleterious for normal development and are associated with cancer-predisposing syndromes.SUFU encodes a component of the sonic hedgehog (SHH, MIM 600725)/patched (PTCH, MIM 601309) signaling pathway. Mutations in genes encoding components of this pathway are deleterious for normal development and are associated with cancer-predisposing syndromes (e.g., HPE3, MIM 142945, BCNS, MIM 109400, and GCPS, MIM 175700).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Gene Name: Suppressor of fused homolog (Drosophila)
Alternative Symbols: SUFUH, JBTS32, SUFUXL, PRO1280
Protein Name: Suppressor of fused homolog
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分子量
- 54kDa
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基因ID
- 51684
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NCBI登录号
- NP_057253
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UniProt
- Q9UMX1
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途径
- Hedgehog Signaling, Tube Formation, Maintenance of Protein Location
抗原
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