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PIAS4 抗体 (N-Term)

Cited in 1 publication. This 兔 多克隆 anti-PIAS4 antibody specifically detects PIAS4 in WB. The antibody is reactive with 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马 和 斑马鱼 samples.
产品编号 ABIN2777708
发货至: 中国
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Quick Overview for PIAS4 抗体 (N-Term) (ABIN2777708)

抗原

See all PIAS4 抗体
PIAS4 (Protein Inhibitor of Activated STAT, 4 (PIAS4))

适用

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人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 斑马鱼

宿主

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克隆类型

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多克隆

标记

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This PIAS4 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    AKNMVMSFRV SDLQMLLGFV GRSKSGLKHE LVTRALQLVQ FDCSPELFKK

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 79%

    产品特性

    This is a rabbit polyclonal antibody against PIAS4. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human PIAS4
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 510 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Zhang, Xu, Han, Wei, Shu: "PIASy represses TRIF-induced ISRE and NF-kappaB activation but not apoptosis." in: FEBS letters, Vol. 570, Issue 1-3, pp. 97-101, (2004) (PubMed).

  • 抗原

    PIAS4 (Protein Inhibitor of Activated STAT, 4 (PIAS4))

    别名

    PIAS4

    背景

    PIAS4 is an inhibitor of TRIF-induced ISRE and NF-kappaB activation. Its mRNA is selectively expressed in endothelial cells, and its expression can be regulated by angiogenic growth factors
    Alias Symbols: PIASY, Piasg, ZMIZ6
    Protein Interaction Partner: HNF4A, HIC1, IKBKG, UBE2I, VHL, SUMO1, SUMO2, PDE4D, PDE4A, MECOM, UBC, SKIL, SERPINA5, OAZ1, SMAD7, SMAD1, LAMP2, KRT18, IRF7, IRF3, IL15RA, FTH1, ESRRA, TICAM1, ZNF512B, PHF11, PHGDH, MPRIP, HNRNPUL1, OPTN, PDE4DIP, PIAS2, BTAF1, ALDOA, ACTN1, PLAG1, Ga
    Protein Size: 510

    分子量

    57 kDa

    基因ID

    51588

    NCBI登录号

    NM_015897, NP_056981

    UniProt

    Q8N2W9

    途径

    JAK/STAT Signaling, Interferon-gamma Pathway, Positive Regulation of Response to DNA Damage Stimulus
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