PPARD 抗体 (Middle Region)
Quick Overview for PPARD 抗体 (Middle Region) (ABIN2777643)
抗原
See all PPARD 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- NPQVADLKAF SKHIYNAYLK NFNMTKKKAR SILTGKASHT APFVIHDIET
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预测反应
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 92%, Human: 100%, Mouse: 92%, Rabbit: 93%, Rat: 100%, Zebrafish: 92%
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产品特性
- This is a rabbit polyclonal antibody against PPARD. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human PPARD
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anti-Peroxisome Proliferator-Activated Receptor delta (PPARD) (AA 1-361) antibody
PPARD 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 4E3-1B11 unconjugated
anti-Peroxisome Proliferator-Activated Receptor delta (PPARD) (C-Term) antibodyVerified PPARD 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Peroxisome Proliferator-Activated Receptor delta (PPARD) (AA 56-165) antibodyPPARD 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1G4 unconjugated
anti-Peroxisome Proliferator-Activated Receptor delta (PPARD) (C-Term) antibodyPPARD 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Peroxisome Proliferator-Activated Receptor delta (PPARD) (AA 102-361) antibodyPPARD 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Peroxisome Proliferator-Activated Receptor delta (PPARD) (N-Term) antibodyPPARD 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Peroxisome Proliferator-Activated Receptor delta (PPARD) (AA 2-100) antibodyPPARD 适用: 人 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Peroxisome Proliferator-Activated Receptor delta (PPARD) antibodyPPARD 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal unconjugated
anti-Peroxisome Proliferator-Activated Receptor delta (PPARD) (AA 260-426) antibodyPPARD 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Peroxisome Proliferator-Activated Receptor delta (PPARD) antibodyPPARD 适用: 人, 小鼠, 大鼠 IF, IHC (p) 宿主: 小鼠 Monoclonal 5F4 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 441 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PPARD (Peroxisome Proliferator-Activated Receptor delta (PPARD))
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别名
- PPARD
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背景
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PPARD is a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear hormone receptors that bind peroxisome proliferators and control the size and number of peroxisomes produced by cells. PPARs mediate a variety of biological processes, and may be involved in the development of several chronic diseases, including diabetes, obesity, atherosclerosis, and cancer. This protein is a potent inhibitor of ligand-induced transcription activity of PPAR delta and PPAR gamma. It may function as an integrator of transcription repression and nuclear receptor signaling. The expression of this gene is found to be elevated in colorectal cancer cells. The elevated expression can be repressed by adenomatosis polyposis coli (APC), a tumor suppressor protein related to APC/beta-catenin signaling pathway. Knockout studies in mice suggested the role of this protein in myelination of the corpus callosum, lipid metabolism, and epidermal cell proliferation.
Alias Symbols: FAAR, NUC1, NUCI, NR1C2, NUCII, PPARB
Protein Interaction Partner: KRTAP10-3, KRTAP10-7, PLA2G4A, CTNNB1, KDM1A, PRMT3, SMAD9, HSP90AA1, TNP1, PSMG1, Nedd4, RANBP9, PRDX6, EIF3I, NCOA1, NR0B2, SHMT2, RXRG, RXRB, RXRA, PROX1, ITGB5, GLUL, RELA, HDAC1, EP300, NCOA2, SRC, SPEN, HDAC7, HDAC3, PEBP1, HDAC2, GADD45G, GADD45B,
Protein Size: 441 -
分子量
- 49 kDa
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基因ID
- 5467
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NCBI登录号
- NM_006238, NP_006229
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UniProt
- Q03181
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途径
- Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Monocarboxylic Acid Catabolic Process, Smooth Muscle Cell Migration, Positive Regulation of fat Cell Differentiation
抗原
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