AKAP8 抗体 (Middle Region)
Quick Overview for AKAP8 抗体 (Middle Region) (ABIN2777567)
抗原
See all AKAP8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- YLKGEDPFTS ETVDPEMEGD DNLGGEDKKE TPEEVAADVL AEVITAAVRA
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预测反应
- Cow: 85%, Dog: 85%, Horse: 92%, Human: 100%, Pig: 92%, Rabbit: 77%
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产品特性
- This is a rabbit polyclonal antibody against AKAP8. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human AKAP8
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 692 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- AKAP8 (A Kinase (PRKA) Anchor Protein 8 (AKAP8))
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别名
- AKAP8
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背景
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The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. AKAP8 is a member of the AKAP family. It is located in the nucleus during interphase and is distinctly redistributed during mitosis. This protein has a cell cycle-dependent interaction with the RII subunit of PKA.The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is located in the nucleus during interphase and is distinctly redistributed during mitosis. This protein has a cell cycle-dependent interaction with the RII subunit of PKA. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: AKAP95, DKFZp586B1222, AKAP-8, AKAP 95, AKAP-95
Protein Interaction Partner: SUMO2, UBC, RPA3, RPA2, RPA1, BMI1, RNF2, EZH2, HIPK4, HDAC11, CSNK2A1, MYC, ESR1, BARD1, LRRK2, CAND1, COPS5, CUL3, HNRNPA1, ELAVL1, Mis12, Aurkb, TADA2A, CASP3, DDX5, PRKAR2A, CCND1, RELA, CCND3, CCND2, MCM2, AMY1C, AMY1A,
Protein Size: 692 -
分子量
- 76 kDa
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基因ID
- 10270
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NCBI登录号
- NM_005858, NP_005849
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UniProt
- O43823
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途径
- SARS-CoV-2 Protein Interactome
抗原
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