FOXP3 抗体 (N-Term)
Quick Overview for FOXP3 抗体 (N-Term) (ABIN2777561)
抗原
See all FOXP3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- PHFMHQLSTV DAHARTPVLQ VHPLESPAMI SLTPPTTATG VFSLKARPGL
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预测反应
- Cow: 100%, Dog: 79%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 86%, Rat: 86%, Sheep: 100%
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产品特性
- This is a rabbit polyclonal antibody against FOXP3. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human FOXP3
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 431 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Naïve rat umbilical cord matrix stem cells significantly attenuate mammary tumor growth through modulation of endogenous immune responses." in: Cytotherapy, Vol. 15, Issue 5, pp. 586-97, (2013) (PubMed).
: "CD25+CD4+ T cells in human cord blood: an immunoregulatory subset with naive phenotype and specific expression of forkhead box p3 (Foxp3) gene." in: Experimental hematology, Vol. 32, Issue 7, pp. 622-9, (2004) (PubMed).
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Naïve rat umbilical cord matrix stem cells significantly attenuate mammary tumor growth through modulation of endogenous immune responses." in: Cytotherapy, Vol. 15, Issue 5, pp. 586-97, (2013) (PubMed).
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- FOXP3 (Forkhead Box P3 (FOXP3))
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别名
- FOXP3
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背景
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Forkhead box protein P3 (FOXP3, Scurfin, Zinc finger protein JM2) encodes a novel member of the forkhead family of transcription factors. It presumably represses transcription, playing a paramount role in determining the amplitude of the response of CD4 T cells to activation
Alias Symbols: JM2, AIID, IPEX, PIDX, XPID, DIETER
Protein Interaction Partner: PRR20A, RBPMS, STUB1, UBC, HSPA1A, IKZF3, GATA3, RUNX1, RELA, NFATC1, HIST1H1B, HDAC1, KAT8, REL, IKZF4, NFAT5, NFATC2, HDAC4, HDAC2, HDAC7, KAT5, HDAC9,
Protein Size: 431 -
分子量
- 47 kDa
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基因ID
- 50943
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NCBI登录号
- NM_014009, NP_054728
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UniProt
- Q9BZS1
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途径
- Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
抗原
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